In-Vitro Lung Model Market Growth Forecast: Exploring Trends and Opportunities for the Next Decade
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How has the in-vitro lung model market grown in recent years?
The market for the in-vitro lung model has seen a significant expansion in recent times. It is projected to increase from $0.44 billion in 2024 to $0.54 billion in 2025, exhibiting a compound annual growth rate (CAGR) of 21.3%. Factors such as the increasing instances of respiratory diseases, heightened emphasis on individualized medicine, renewed interest in drug repurposing, focus on precision medicine methodologies, and heightened awareness about environmental health hazards have contributed to the growth during the historic period.
How is the in-vitro lung model market size expected to evolve during the forecast period?
The market for in-vitro lung models is slated for substantial expansion in the coming years, potentially reaching a considerable size of $1.16 billion by 2029, with a compound annual growth rate of 21.0%. This anticipated increase during the projection period can be credited to various factors such as the necessity for drug development, the escalation in preclinical testing, a heightened understanding of respiratory toxicology, a shift towards regenerative medicine, escalating environmental concerns, and a rise in the elderly population. The forecast period is likely to observe significant trends including a surge in demand for drug testing, progression in 3D printing technology, advancements in organ-on-chip technology, application of artificial intelligence and machine learning, inclusion of sensors and monitoring devices, broadening of usage beyond pharmaceuticals, and the creation of disease-specific models.
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Which key drivers are propelling the in-vitro lung model market’s growth?
The growth of the in vitro lung model market is predicted to be driven by the rise in clinical research. These research studies, which ascertain the efficacy of new medical treatments in humans, are spurred by the growing demand for superior healthcare treatments, elevated healthcare requirements, and the quest for creative remedies to intricate health problems. In vitro lung models facilitate these clinical trials by presenting a regulated setting to examine the impact of compounds on lung tissue. This assists in endeavors such as drug testing, toxicity evaluations, disease modeling, and comprehending disease pathways. For example, data from ClinicalTrials.gov, a clinical trial registry based in the U.S, reveals that by the end of 2023, the number of registered clinical trials worldwide on their site stood at 477,230. This marks an upsurge from the 437,508 trials registered in 2022. Consequently, the escalation in clinical research propels the in vitro lung model market.
What are the market segments in the in-vitro lung model industry?
The in-vitro lung model market covered in this report is segmented –
1) By Type: Two-Dimensional (2D) Model, Three-Dimensional (3D) Model
2) By Application: Drug Discovery And Toxicology Studies, Physiological Research, Three-Dimensional (3D) Model Development, Other Applications
3) By End-User: Academic Research Institutes, Pharmaceutical And Biotechnology Companies, Other End-Users
Subsegments:
1) By Two-Dimensional (2D) Model: Monolayer Cell Cultures, Co-cultures
2) By Three-Dimensional (3D) Model: Spheroids, Organoids, Lung-On-A-chip Models
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Which leading companies are shaping the growth of the in-vitro lung model market?
Major companies operating in the in-vitro lung model market are Thermo Fisher Scientific Inc., Lonza Group AG, PerkinElmer Inc., Charles River Laboratories International Inc., Varian Medical Systems Inc., Epithelix, The Charles Stark Draper Laboratory Inc., STEMCELL Technologies, American Type Culture Collection (ATCC), BioIVT, InSphero, Emulate Inc., PhoenixBio Co. Ltd., Newcells Biotech, CN Bio Innovations Ltd., Mimetas, Cyfuse Biomedical K.K., 3D Biotek LLC, AlveoliX AG, AxoSim Technologies LLC, Elveflow, Hesperos Inc., Kugelmeiers Ag, SynVivo Inc., VITROCELL Systems GmbH
Which trends are expected to transform the in-vitro lung model market?
Leading firms working in the in-vitro lung model industry are advancing their prototypes with the help of 3D respiratory tissue models to increase their physiological relevance and complexity. Through a specialized environment, certain respiratory cells are cultured to form 3D structures that closely resemble the function and structure of the respiratory system providing a more accurate platform for drug testing and research. For example, MatTek Corporation, a biotechnology firm based in the US, launched a unique 3D respiratory tissue model known as EpiNasal, using primary human nasal epithelial cells in April 2023. EpiNasal mimics the three-dimensional structure and functionality of the nasal epithelium, including mucus-producing goblet cells, working tight junctions, and beating cilia. The launch of EpiNasal broadens MatTek’s line of 3D respiratory tissue models. This sophisticated model is an encompassing system for analyzing the impact of consumer products, pharmaceuticals, pathogens, and chemicals on the human respiratory system.
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Which geographic areas are influencing the growth of the in-vitro lung model market?
North America was the largest region in the in-vitro lung model market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro lung model market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
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