Growth Opportunities and Trends in the Locally Advanced Pancreatic Cancer Market: Key Insights for 2025-2034
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How Will the CAGR of the Locally Advanced Pancreatic Cancer Market Influence Its Overall Growth by 2034?
The market size for locally advanced pancreatic cancer has seen significant expansion in the recent past. From 2024 to 2025, it is projected to increase from $0.95 billion to $1.05 billion, with a compound annual growth rate (CAGR) of 10.9%. This growth during the historic period can be linked to a rise in awareness about pancreatic cancer, the implementation of improved chemotherapy methods, a surge in the utilization of targeted therapies, an increase in incidences of pancreatic cancer, the creation of combination treatment plans, and improvements in supportive care choices.
In the coming years, the local advanced pancreatic cancer market is anticipated to experience swift expansion. Growth projections indicate an increase to $1.57 billion by 2029, with a Compound Annual Growth Rate (CAGR) of 10.5%. This significant growth during the forecast period can be primarily traced back to heightened cancer awareness, improved chemotherapeutic methods, increased usage of targeted therapies, and rising occurrences of pancreatic cancer. Further factors are the evolution of combined treatment protocols and improved options for supportive care. Key trends in the pipeline for this forecast period include progress in immunotherapy, creation of novel targeted therapies, advancements in precision radiation practices, improved diagnostic imaging techniques, preference for less invasive surgical procedures, integration of artificial intelligence in devising treatment plans, and advancements in treatment combination approaches.
Which Major Market Drivers Are Expected to Boost the Locally Advanced Pancreatic Cancer Market’s Growth Potential?
The growth of the markets for locally advanced pancreatic cancer is forecasted to be propelled by the escalating usage of tobacco. The tobacco plant’s leaves are utilized in the manufacturing of products like cigars and cigarettes. These products contain nicotine, an addictive substance that can lead to severe health complications such as heart disease and cancer. Factors that contribute to the increase in tobacco usage could be its easy accessibility, affordability, marketing of tobacco, its acceptance in certain social circles, and stress-induced smoking. The consumption of tobacco is a primary risk factor for the emergence of locally advanced pancreatic cancer as it leads to a rise in pancreatic malignancies. As per the research by the US-based nonprofit organization focused on ending the smoking epidemic, Global Action to End Smoking, it was reported in 2024 that in 2022, about 62.9 million American adults were using tobacco, placing the U.S. at 4th position globally and topmost in the Americas. Moreover, roughly 11.5% of American adults, equating to 28.3 million, were cigarette smokers, with the percentage being higher among men (13.1%) as compared to women (10.1%). Hence, the escalating usage of tobacco is facilitating the growth of the market for locally advanced pancreatic cancer.
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Who Are the Leading Companies Pioneering Change in the Locally Advanced Pancreatic Cancer Market?
Major companies operating in the locally advanced pancreatic cancer market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck KGaA, AbbVie Inc., Bayer Inc., Bristol-Myers Squibb Company, AstraZeneca plc, Abbott Laboratories, Novartis AG, GSK plc, Ipsen Biopharmaceuticals Inc., Lupin Limited, NovoCure Limited, Theratechnologies Inc., XBiotech, Prestige Biopharma, OSE Immunotherapeutics, Helix Biopharma Corporation, Fawn Incorporation, Eli Lilly and Co
What Are the Most Significant Trends Transforming the Locally Advanced Pancreatic Cancer Market Today?
Prominent firms in the locally advanced pancreatic cancer market are concentrating on the creation of innovative solutions such as orphan drugs, aiming to optimize treatment methods, enhance patient prognosis, and fulfil the unaddressed healthcare requirements related to this severe illness. Orphan drugs, targeted at treating rare conditions impacting a minimal population, enjoy encouragement from regulatory bodies through incentives like tax deductions and exclusive market rights, further facilitating their development. As an example, in January 2025, Actuate Therapeutics Inc., an American biopharmaceutical enterprise, declared that its Elraglusib, a novel GSK-3ß inhibitor, has been granted Orphan Drug Designation by both the European Medicines Agency (EMA) and US Food and Drug Administration (FDA) for treatment of pancreatic ductal adenocarcinoma (PDAC) (a likely type of locally advanced pancreatic cancer). This acknowledgment underscores its potential to bridge a crucial gap in combating this grave cancer, particularly following encouraging Phase 2 trial outcomes that demonstrated substantial clinical progression and anti-tumor impacts in metastatic PDAC patients.
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What Are the Primary Segments of the Locally Advanced Pancreatic Cancer Market and Their Roles in Growth Dynamics?
The locally advanced pancreatic cancer market covered in this report is segmented –
1) By Therapy: Chemotherapy, Immunotherapy, Radiation Therapy, Surgery
2) By Route Of Administration: Oral, Injectables, Other Route Of Administrations
3) By End-User: Hospital, Specialty Clinics, Research Institutions, Other End-Users
Subsegments:
1) By Chemotherapy: Gemcitabine-based Chemotherapy, FOLFIRINOX Chemotherapy
2) By Immunotherapy: Immune Checkpoint Inhibitors, Cancer Vaccines
3) By Radiation Therapy: External Beam Radiation Therapy, Stereotactic Body Radiation Therapy (SBRT)
4) By Surgery: Pancreaticoduodenectomy (Whipple Procedure), Distal Pancreatectomy, Total Pancreatectomy
Which Regions Are Leading the Charge in Locally Advanced Pancreatic Cancer Market Development?
North America was the largest region in the locally advanced pancreatic cancer market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the locally advanced pancreatic cancer market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
How Is the Definition of the Locally Advanced Pancreatic Cancer Market Impacting Future Growth?
Locally advanced pancreatic cancer (LAPC) refers to a stage of pancreatic cancer where the tumor is confined to the pancreas and surrounding tissues but has not spread to distant organs. This cancer is usually not suitable for surgical removal due to its involvement with vital blood vessels or nearby structures.
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