2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What Factors Are Propelling the Market Growth of theNecrotizing Enterocolitis Market from 2025 to 2034?

The escalation in premature birth incidents is anticipated to boost the necrotizing enterocolitis market’s expansion moving forward. Preterm births, also called premature births, are defined as the delivery of a baby prior to 37 weeks of gestation in contrast to the normal 40-week pregnancy term. The surge in premature births can be attributed to maternal health issues like hypertension, diabetes, and infections that enhance preterm labor’s risk. Lifestyle components such as smoking, drug consumption, and inadequate nutrition also heighten the chances of early births. The increase in premature births results in more instances of necrotizing enterocolitis (NEC) since premature babies possess underdeveloped gastrointestinal systems, which elevates their vulnerability to inflammation and infection. For example, in January 2024, based on data from the Centers for Disease Control and Prevention, a governmental agency in the US, premature births represented 8.67% of total annual births in the United States. Hence, the rising number of premature births catalyze the growth of the necrotizing enterocolitis market.

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#What Long-Term Growth Rate is Expected for theNecrotizing Enterocolitis Market Between 2025 and 2034?

In recent times, there has been a robust expansion in the necrotizing enterocolitis market, with its size projected to inflate from $4.83 billion in 2024 to $5.16 billion in 2025, marking a compound annual growth rate (CAGR) of 6.8%. Factors contributing to the marked growth in the historical period include the escalating incidences of necrotizing enterocolitis, swelling populations, growth in per capita income, increased government funding, and a rise in premature birth cases.

Over the upcoming years, the necrotizing enterocolitis market is projected to grow significantly reaching $6.62 billion by 2029 with a compound annual growth rate (CAGR) of 6.4%. The increase for this period is likely due to factors such as the escalating healthcare costs, growing cases and prevalence of ulcerative colitis (UC), a rise in gastrointestinal diseases, a surge in elderly and obese populace, as well as the expanding aged population. Key trends anticipated within this forecast period are advancements in research of biomarkers for early detection of NEC, progress in non-invasive testing methods, wider adoption of modern monitoring systems, improvements in surgical techniques, and the emergence of targeted therapies.

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How Are Market Trends and Innovations Revolutionizing the Necrotizing Enterocolitis Industry in Recent Times?

Leading businesses in the necrotizing enterocolitis market are concentrating on the creation of innovative product solutions, such as cell-free sterile biologic solutions, in an effort to address the urgent need for effective treatments and to enhance premature infant outcomes. A cell-free sterile biologic solution is a cleansed, sterile liquid composed of bioactive molecules like proteins, growth factors, and cytokines, derived from cultured cells but devoid of intact cells. The solution is designed to advance the healing process and minimize inflammation. For example, in December 2023, American biopharmaceutical company Noveome Biotherapeutics, Inc. was given approval from the U.S. Food and Drug Administration (FDA) to proceed with Phase 1-2 clinical trials of ST266, a new biologic designed to treat necrotizing enterocolitis (NEC) in premature infants. This represents a significant achievement since the introduction of ST266 is expected to be the first major therapeutic development for NEC in over three decades, meeting an urgent healthcare need, considering the disease lethality and high rates of morbidity in susceptible populations.

Which Key Market Players Are Shaping the Future and Growth of theNecrotizing Enterocolitis Market?

Major companies operating in the necrotizing enterocolitis market are Abbott Laboratories, Astellas Pharma Inc., Mayo Foundation for Medical Education and Research, Cleveland Clinic, Boston Children’s Hospital, Hollister Incorporated, UPMC Children’s Hospital of Pittsburgh, Prolacta Bioscience Inc., Evolve BioSystems, Sigma-Tau Pharmaceuticals, Mead Johnson & Company LLC, Liminal BioSciences Inc., Noveome Biotherapeutics Inc., Infant Bacterial Therapeutics, Prometic Life Sciences Inc., Nexilico, Siolta Therapeutics, ProThera Biologics Inc., Plakous Therapeutics Inc., Chosen Diagnostics Inc.

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What Are the Core Segments of the Necrotizing Enterocolitis Market, and How Do They Contribute to Growth?

The necrotizing enterocolitis market covered in this report is segmented –

1) By Treatment: Total Parenteral Nutrition (TPN), Gastrointestinal Decompression, Antimicrobial Therapy, Antifungal Treatment, Paracentesis, Other Treatments

2) By Diagnosis: Laboratory Tests, Imaging Techniques

3) By Stage: Stage I (Suspected Necrotizing Enterocolitis), Stage II (Definite Necrotizing Enterocolitis), Stage III (Advanced Necrotizing Enterocolitis)

4) By Distribution Channel: Direct Tender, Hospital Pharmacy, Retail Pharmacy, Online Pharmacy, Other Distribution Channels

5) By End-User: Hospitals, Neonatal Intensive Care Units (NICUs), Specialty Clinics

Subsegments:

1) By Total Parenteral Nutrition (TPN): Standard TPN Formulations, Customized Or Individualized TPN Solutions, Lipid Emulsions for TPN, Protein And Amino Acid Supplements In TPN, Micronutrient And Electrolyte-Enhanced TPN

2) By Gastrointestinal Decompression: Nasogastric Tube (NG Tube) Decompression, Orogastric Tube Decompression, Surgical Gastrostomy for Decompression, Non-Surgical Decompression Techniques

3) By Antimicrobial Therapy: Broad-Spectrum Antibiotics, Gram-Positive Coverage Antibiotics, Gram-Negative Coverage Antibiotics, Combination Antibiotic Therapy, Prophylactic Antibiotic Strategies For High-Risk Neonates

4) By Antifungal Treatment: Systemic Antifungal Therapy, Prophylactic Antifungal Therapy For Preterm Infants, Combination Antifungal And Antibiotic Therapy For Severe NEC

5) By Paracentesis: Diagnostic Paracentesis, Therapeutic Paracentesis, Guided Paracentesis using Ultrasound Or Radiological Techniques

6) By Other Treatments: Probiotics And Prebiotics for NEC Prevention, Surgical Interventions, Stem Cell Therapy And Regenerative Medicine Approaches, Immunomodulatory Therapies, Supportive Care

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What Regions Are Dominating the Necrotizing Enterocolitis Market Growth?

North America was the largest region in the necrotizing enterocolitis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the necrotizing enterocolitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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