Global Nucleic Acid Based Gene Therapy Market
Medical Equipment

Understand How The Nucleic Acid Based Gene Therapy Market Is Poised To Grow Through 2024-2033

The Business Research Company’s global market reports are now updated with the latest market sizing information for the year 2023 and forecasted to 2032

As per The Business Research Company’s Nucleic Acid Based Gene Therapy Global Market Report 2023, the nucleic acid based gene therapy market is expected to show significant growth in the forecast period.

The nucleic acid-based gene therapy market has demonstrated robust growth, escalating from $0.75 billion in 2023 to $0.82 billion in 2024 at a substantial compound annual growth rate (CAGR) of 9.6%. Projections indicate continued expansion, reaching $1.2 billion in 2028 with a CAGR of 10.1%. This blog explores the driving forces behind this growth, major trends, and the impactful role of healthcare expenditure and strategic collaborations in shaping the future of nucleic acid-based gene therapy.

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Healthcare Expenditure’s Impact on Market Growth

Healthcare Expenditure Overview

  • Rising healthcare expenditure is anticipated to propel the nucleic acid gene therapy market.
  • Healthcare expenditure encompasses spending on healthcare-related goods and services within a given healthcare system or economy.

Canadian Institute for Health Information Statistics

  • In November 2022, healthcare expenditure in Canada rose to 0.8%, amounting to $331 billion.
  • A significant increase from 7.6% in 2021 showcases the pivotal role of healthcare spending in driving the nucleic acid gene therapy market.

Market Players

  • Key companies in the nucleic acid-based gene therapy market include Celsion Corporation, Wave Life Sciences, Imugene Ltd., and others.
  • Rising healthcare expenditure supports the development and accessibility of nucleic acid gene therapy.

Strategic Collaborations and Partnerships Driving Production Excellence

Importance of Collaborations

  • Companies focus on strategic partnerships and collaborations to enhance production capabilities.
  • Collaboration allows major players to expand their market reach and leverage shared resources.

Pfizer and Beam Therapeutics Collaboration

  • In January 2022, Pfizer Inc. and Beam Therapeutics Inc. announced an exclusive four-year research collaboration.
  • Focused on in vivo base editing programs targeting rare genetic diseases of the liver, muscle, and central nervous system.

Merck and Orna Therapeutics Partnership

  • In August 2022, Merck and Orna Therapeutics entered a collaboration agreement.
  • The partnership aims to discover, develop, and commercialize multiple programs, including vaccines and therapeutics for infectious diseases and oncology.

Market Segmentation and Regional Dominance

Market Segmentation

  1. By Technology:
    • Anti-Sense and Anti-Gene
    • Short Inhibitory Sequences
    • Gene Transfer Therapy
    • Nucleoside Analogs
    • Ribozymes
    • Aptamers
    • Other Technologies
  2. By Application:
    • Oncology
    • Muscular Dystrophy/Muscular Disorders
    • Rare Diseases
  3. By End User:
    • Hospitals and Clinics
    • Academic and Research Institutes

Regional Dominance

  • In 2023, North America emerged as the largest region in the nucleic acid-based gene therapy market.
  • The region’s advanced healthcare infrastructure and robust research and development activities contribute to market leadership.

Future Trends in Nucleic Acid-Based Gene Therapy

Ex Vivo Gene Editing

  • Advancements in ex vivo gene editing technologies enhance precision.
  • Targeted modifications before reintroducing genetic material to the patient.

Advances in In Vivo Gene Editing

  • Ongoing innovations in in vivo gene editing techniques.
  • Direct editing of genes within the patient’s body for improved therapeutic outcomes.

Combination Therapies

  • Growing emphasis on combining gene therapies for enhanced effectiveness.
  • Combination therapies address multiple aspects of complex diseases.

Targeted Delivery Systems

  • Development of targeted delivery systems for improved therapeutic outcomes.
  • Precise delivery of gene therapies to specific cells or tissues.

Gene Editing for Rare Diseases

  • Increasing focus on gene editing techniques for treating rare diseases.
  • Customized therapies addressing the unique genetic makeup of individuals with rare conditions.

Non-Viral Vectors

  • Adoption of non-viral vectors as alternatives to traditional viral vectors.
  • Non-viral vectors offer advantages in safety and ease of production.

Conclusion

In conclusion, the nucleic acid-based gene therapy market is on a trajectory of rapid growth, driven by factors such as healthcare expenditure, strategic collaborations, and advancements in gene therapy technologies. The strategic partnerships between major companies, like Pfizer and Beam Therapeutics, underscore the importance of shared resources in advancing gene therapy research and development. As the market continues to expand, the focus on precision editing, combination therapies, and targeted delivery systems reflects a commitment to advancing therapeutic outcomes for various diseases. The future of nucleic acid-based gene therapy holds promise, with ongoing research and development paving the way for innovative and personalized treatment options.

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