2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

How Are Key Drivers in the Industry Acting as Catalysts for the Growth of theOligonucleotide Synthesis Market?

The increase in chronic diseases is predicted to drive the growth of the oligonucleotide synthesis market. Chronic diseases are defined as conditions that persist for over a year and need ongoing medical care, which could potentially worsen with time. Oligonucleotides have the ability to affect the gene expression responsible for chronic diseases through various ways. They have the potential to target mRNA, pre-mRNA, or non-coding RNA to control splicing events, stimulate degradation or disrupt protein translation. For example, the World Health Organization, a specialized agency of the United Nations based in Switzerland, reported in September 2022 that out of the 41 million global deaths, 74% were due to non-communicable diseases (NCDs) or chronic diseases. The report further detailed that there were 17.9 million deaths from cardiovascular diseases, 9.3 million deaths from cancer, 4.1 million deaths resulting from chronic respiratory diseases, and 2.0 million deaths from diabetes. Hence, the escalating prevalence of chronic and rare diseases is fuelling the growth of the oligonucleotide synthesis market.

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#What Are the Key Projections for the CAGR of the Oligonucleotide Synthesis Market From 2025 to 2034?

The market size of oligonucleotide synthesis has seen quick expansion in the past few years. The market is expected to swell from $10.33 billion in 2024 to $11.94 billion in 2025, marking a compound annual growth rate (CAGR) of 15.6%. The historical period’s growth is closely related to improvements in biomedical research, advancements in therapeutic development, innovative strides in biotechnology, genomic investigations, and the steady surge in DNA technologies.

The market for oligonucleotide synthesis is forecasted to expand considerably in the years to come. Its value is set to reach $22.29 billion by 2029, with a compound annual growth rate (CAGR) of 16.9%. This growth during the forecast period is influenced by the introduction of new diagnostic tools, RNA interference (RNAi) treatments, regenerative medicine, nanotechnology uses, and gene editing advancements. The forecast period will likely see trends such as targeted drug creation, innovative distribution systems, automated synthesis, CRISPR-cas technology, and next-generation sequencing (NGS).

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What Are the Current Market Growth and Trends in the Oligonucleotide Synthesis Market That Industry Players Should Watch?

The primary trend that is becoming increasingly prominent in the oligonucleotide synthesis market is product innovation. To maintain their market standing, major firms are creating inventive products. As an example, Ansa Biotechnologies, Inc., an American company that specializes in manufacturing complex DNA, launched Ansa Clonal DNA and Ansa DNA Fragments in July 2024. Ansa Clonal DNA offers clonal, flawless sequences of DNA up to 600 base pairs long, negating the need for assembly, and providing superior accuracy for intricate synthetic biology projects. This product guarantees errorless, ready-to-use DNA sequences thereby rendering it a trustworthy choice for scientists. Similarly, Ansa DNA Fragments provide sequence-verified linear double-stranded DNA fragments, up to 600 base pairs as well, designed for assorted research uses. Utilizing their pioneering enzymatic synthesis technique, Ansa consistently produces complex DNA structures, inclusive of repeats and secondary structures, with great accuracy.

What Are the Major Market Players Making an Impact on theOligonucleotide Synthesis Market Growth?

Major companies operating in the oligonucleotide synthesis market include Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, GE HealthCare Technologies Inc., Eurofins Scientific SE, Agilent Technologies Inc., Nitto Denko Avecia Inc., Alnylam Pharmaceuticals Inc., Maravai Life Sciences, LGC Limited, Ionis Pharmaceuticals Inc., GenScript Inc., Ajinomoto Bio-Pharma Services, Sarepta Therapeutics Inc., Integrated DNA Technologies Inc., Twist Bioscience Corporation, Eurogentec SA, Kaneka Eurogentec S.A., Biocomma Limited, Bio-Synthesis Inc., TriLink BioTechnologies Incorporated, Generi Biotech s.r.o., ATDBio Ltd., BioAutomation Corporation, Biolegio B.V., Dharmacon Research Inc.

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How Are the Key Segments of the Oligonucleotide Synthesis Market Driving Opportunities and Innovations?

The oligonucleotide synthesis market covered in this report is segmented –

1) By Type: Custom Oligos, Predesigned Oligos

2) By Product Type: Oligonucleotides, Reagents, Equipment, Services, Purification, Modification

3) By Application: Therapeutic Applications, Research Applications, Diagnostic Applications

Subsegments:

1) By Custom Oligos: Long Oligonucleotides, Short Oligonucleotides, Modified Oligonucleotides

2) By Predesigned Oligos: Gene-Specific Oligos, Probe Oligos, Primers For PCR And RT-PCR

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What Regions Are At the Forefront of #How Are Key Drivers in the Industry Acting as Catalysts for the Growth of theOligonucleotide Synthesis Market?# Market Expansion?

North America was the largest region in the oligonucleotide synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the oligonucleotide synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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