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What are the Key Projections for the CAGR of the Oncolytic Virus Therapy Market From 2025 to 2034?

The oncolytic virus therapy market has witnessed exponential growth in recent years. It is projected to increase from $0.19 billion in 2024 to $0.23 billion in 2025, at a CAGR of 25.4%. This expansion has been driven by advancements in genetic engineering techniques, a deeper understanding of tumor microenvironments, clinical successes and regulatory approvals, the rise of immunotherapy in cancer treatment, and progress in gene delivery systems.

The oncolytic virus therapy market is forecasted to grow exponentially, reaching $0.55 billion by 2029 with a CAGR of 23.7%. Growth will be driven by the expansion of oncolytic virus platforms, the emergence of combination therapies with immune checkpoint inhibitors, advancements in personalized medicine, an increasing number of clinical trials, and favorable regulatory guidelines. Major trends will include innovations in delivery systems, progress in synthetic biology, collaborations within the biopharmaceutical sector, breakthroughs in virology and immunology, and a heightened focus on pediatric oncology.

What External and Internal Drivers Are Contributing to the Growth of the oncolytic virus therapy Market’s Growth?

The growing prevalence of cancer is also expected to boost the oncolytic virus therapy market. Oncolytic virus therapy aims to selectively target and destroy cancer cells while stimulating an immune response. According to the American Cancer Society, there will be 1,958,310 new cancer cases and 609,820 cancer-related deaths in the U.S. in 2023. The increasing cancer prevalence is fostering the growth of the oncolytic virus therapy market.

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What Are the Key Industry Players Leading the Charge in the Oncolytic Virus Therapy Market’s Growth?

Major companies operating in the oncolytic virus therapy market include:

• Pfizer Inc._x000D_

• Johnson & Johnson_x000D_

• Sorrento Therapeutics Inc._x000D_

• AbbVie Inc._x000D_

• AstraZeneca plc_x000D_

How Are Market Trends and Shifts Impacting the Growth Trajectory of the Oncolytic Virus Therapy Market?

In the oncolytic virus therapy market, major companies are focusing on obtaining regulatory approvals to accelerate the introduction of innovative cancer treatments. For example, in March 2024, ImmVira, a China-based biotechnology company, received Fast Track designation from the FDA for its oncolytic virus therapy, MVR-T3011 IT. This therapy targets recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) in patients who have not responded to previous treatments, expediting the development and review process for therapies addressing unmet medical needs.

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What Are the Key Components of the Oncolytic Virus Therapy Market, and How Do Its Segments Perform?

The oncolytic virus therapy market covered in this report is segmented –

1) By Therapy Type: HSV-Based Oncolytic Virus Therapy, Adenovirus-Based Oncolytic Virus Therapy, Reovirus, Poxviruses, NDV (Newcastle Disease Virus), Other Therapy Types

2) By Virus Type: Genetically Engineered Oncolytic Viruses, Oncolytic Wild-Type Viruses

3) By Application: Breast Cancer, Lung Cancer, Prostate Cancer, Melanoma, Brain Tumor, Blood Cancer

4) By End-User: Hospitals, Specialty Clinics, Cancer Research Institutes

Subsegments:

1) By HSV-Based Oncolytic Virus Therapy: Talimogene Laherparepvec (T-VEC), Other HSV-Based Therapies

2) By Adenovirus-Based Oncolytic Virus Therapy: Onyx-015, AdV-5/3-D24, Other Adenovirus-Based Therapies

3) By Reovirus: Reolysin, Other Reovirus Therapies

4) By Poxviruses: JX-594 (OncoVac), Other Poxvirus Therapies

5) By NDV (Newcastle Disease Virus): NDV-Based Therapies, Other NDV Applications

6) By Other Therapy Types: Combination Therapies, Other Emerging Oncolytic Virus Therapies

What Regions Are Influencing the Dynamics of the Oncolytic Virus Therapy Market?

North America was the largest region in the oncolytic virus therapy market in 2024 and is expected to be the fastest-growing region in the forecast period. The regions covered in the oncolytic virus therapy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

What Key Elements Shape the Definition of the Oncolytic Virus Therapy Market?

Oncolytic virus therapy, also known as virotherapy, is a type of cancer treatment that utilizes viruses to target and destroy cancer cells in the body. The main objective of oncolytic virus therapy is to use viruses that have been genetically modified or naturally occur in a way that allows them to selectively infect and replicate within cancer cells while sparing healthy cells.

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