2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What Factors Are Propelling the Market Growth of theOnpattro Market from 2025 to 2034?

The increasing prevalence of hereditary transthyretin-mediated amyloidosis is expected to propel the growth of the Onpattro market. Hereditary transthyretin-mediated amyloidosis (hATTR) is a rare genetic disorder that causes harmful protein deposits affecting nerves and the heart. Onpattro treats hATTR by silencing the TTR gene to reduce amyloid protein production. For instance, a report by Verywell Health in February 2024 estimated that 5,500–38,500 people globally are affected by hATTR, with significant underdiagnosis. Therefore, the growing prevalence of hATTR is driving the Onpattro market.

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How Will the Growth Rate of theOnpattro Market Impact Industry Trends by 2034?

The onpattro market size has XX (HCAGR) in recent years. It will grow from $XX million in 2024 to $XX million in 2025 at a compound annual growth rate (CAGR) of XX%. Contributing factors include rising hereditary ATTR amyloidosis cases, awareness of rare diseases, more R&D funding, an aging population, and growing healthcare spending.

The onpattro market size is expected to grow at a CAGR of XX%, reaching $XX million by 2029. Growth is attributed to collaborations and licensing, regulatory support, increasing rates of chronic diseases, the growth of biopharmaceutical collaborations, and the rising prevalence of transthyretin amyloidosis. Trends include greater adoption of RNA-based therapies, orphan drug designations, integration of digital health tools, a shift to personalized medicine, and technological advances in drug delivery.

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How Are Market Trends and Innovations Revolutionizing theOnpattro Industry in Recent Times?

A key trend in the onpattro market is extending its indications through supplemental drug applications. In February 2023, Alnylam Pharmaceuticals, a US-based firm, had its Supplemental New Drug Application (sNDA) accepted for ONPATTRO (patisiran) to treat cardiomyopathy linked to transthyretin amyloidosis (ATTR). ONPATTRO is an RNA interference therapy targeting the TTR protein. Initially approved in 2018 for polyneuropathy in hereditary ATTR, the expansion is supported by Phase III APOLLO-B results showing improved functional capacity and quality of life in cardiomyopathy patients.

Which Key Market Players Are Shaping the Future and Growth of theOnpattro Market?

Major companies operating in the onpattro market include Alnylam Pharmaceuticals Inc.

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What Are the Core Segments of the Onpattro Market, and How Do They Contribute to Growth?

The onpattro market covered in this report is segmented –

1) By Clinical Indication: Hereditary Transthyretin-Mediated Amyloidosis, Wild-Type Transthyretin Amyloidosis, Other Transthyretin-Related Amyloidoses

2) By Distribution Channel: Direct Sales, Pharmacies, Online Pharmacies

3) By End User: Hospitals, Specialty Clinics, Home Healthcare Providers

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What Regions Are Dominating the Onpattro Market Growth?

North America was the largest region in the onpattro market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the onpattro market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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