Global oral biologics & biosimilars Market
Pharmaceuticals

The Road Ahead for the Oral Biologics & Biosimilars Market: Key Growth Trends and Opportunities to Watch

Updated 2025 Market Reports Released: Trends, Forecasts to 2034 – Early Purchase Your Competitive Edge Today!

What CAGR is Anticipated for the Oral Biologics & Biosimilars Market During the Forecast Period, and Why?

In recent times, there has been remarkable growth in the oral biologics & biosimilars market. The market, which was valued at $7.04 billion in 2024, is projected to rise to $8.69 billion in 2025, marking a compound annual growth rate (CAGR) of 23.5%. Several factors have driven growth in the previous years, including enhanced cooperation and partnerships among market players yielding better insights, an increased demand for immunology, the demand driven by the cost-effectiveness of the manufacturing process, a rise in the aging population, government policies and the market’s ability to set lofty prices.

The market size for oral biologics & biosimilars is predicted to witness a dramatic increase in the coming years, expanding to $19.13 billion by 2029 with a compound annual growth rate (CAGR) of 21.8%. This projected growth during the forecast period is due to several factors including, strong research and development efforts towards oral biologics creation, preference towards pills instead of injections, embracing unhealthy living habits, progress in technology, convenience in using oral biologics, improved accessibility to healthcare, biologics compensation, increase in biosimilars, and a growing incidence of chronic illnesses. In this anticipated period, key trends include investing in the oral biologics sector for potential high-profit margins, leaning towards biologics due to increasing innovation in the field, and the development of drugs based on microneedle injectors to enhance bioavailability while reducing the side effects associated with the subcutaneous route.

What Are the Primary Drivers Supporting the Growth of the oral biologics & biosimilars Market?

The escalating occurrence of chronic illnesses such as arthritis, asthma, and cancer is predicted to fuel the expansion of the oral biologics and biosimilar market. Extended working hours, restricted physical fitness, and poor dietary and drinking patterns increase the incidence of chronic diseases. Biologics, which are being used more frequently to manage these conditions, trigger the immune system to target cancerous cells, assisting the body’s inherent defensive mechanisms in eliminating the cells causing the disease. As per a United Nations report by a US-based intergovernmental institution, by 2030, it is forecasted that chronic diseases will cause 70% of all deaths globally and almost 60% of all global deaths will be due to chronic diseases. Hence, the surge in chronic disease cases is propelling the growth of the biologics and biosimilar market.

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Which Companies Are Poised to Shape the Future of the Oral Biologics & Biosimilars Market?

Major companies operating in the oral biologics & biosimilars market include:

• Merck & Co. Inc._x000D_

• GlaxoSmithKline_x000D_

• Novo Nordisk_x000D_

• ALK-Abelló_x000D_

• Aimmune Therapeutics Inc._x000D_

What Are the Latest Innovations and Trends Influencing the Oral Biologics & Biosimilars Market?

The increasing development of novel insulin biosimilars is an emerging trend in the oral biologics and biosimilar market. The existing market giants are delving into the production of an insulin biosimilar replica to enhance their market footprint. For instance, In January 2023, the US-based biotechnology firm, Amgen, introduced Amjevita, which is a biosimilar to Humira, reflecting advancements in devising insulin biosimilars. Their objective is to diminish expenses and enhance the accessibility of crucial therapies. Amjevita provides a more budget-friendly alternative for ailments such as arthritis and Crohn’s disease, making insulin biosimilars for diabetes treatments more reasonably priced and readily available. Such progressions are fuelling competition and encouraging innovation in biologics. The enterprise primarily concentrates on the exploration, evolution, manufacturing, and distribution of groundbreaking human therapeutics.

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How Are Market Segments in the Oral Biologics & Biosimilars Industry Positioned for Long-Term Growth?

The oral biologics & biosimilars market covered in this report is segmented –

1) By Therapy: Lymphocyte Modulators, Interleukin Inhibitors, Tumor Necrosis Factor-Alpha Inhibitors, Immunostimulants, GPCR Modulators, Other Tharpies

2) By Disease: Diabetes, Arthritis and Crohn’s Disease, Cancer, Infectious Disease, Other Autoimmune Disease, Other Diseases

3) By Molecule Type: Vaccines, Proteins and Peptides, Monoclonal Antibodies, Other Molecule Types

4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:

1) By Lymphocyte Modulators: T-Cell Modulators, B-Cell Modulators, Sphingosine-1-Phosphate Receptor Modulators

2) By Interleukin Inhibitors: IL-1 Inhibitors, IL-6 Inhibitors, IL-17 Inhibitors, IL-23 Inhibitors

3) By Tumor Necrosis Factor-Alpha Inhibitors: TNF-a Blockers, Monoclonal Antibodies Targeting TNF-a

4) By Immunostimulants: Cytokines, Immune Checkpoint Inhibitors, Adjuvants

5) By GPCR Modulators: Agonists, Antagonists, Biased Ligands

6) By Other Therapies: Cell-Based Therapies, Gene Therapies, Combination Therapies

What Regions Are Contributing Significantly to the Growth of the Oral Biologics & Biosimilars Market?

North America was the largest region in the oral biologics and biosimilar drugs market in 2024. The Middle East is expected to be the fastest-growing region in the forecast period. The regions covered in the oral biologics & biosimilars market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

How Is the Definition of the Oral Biologics & Biosimilars Market Impacting Future Growth?

Biologics are drugs made from living cells using highly complex technology, while biosimilars are created to function similarly to biologics but are not identical to biologics. The oral biologics and biosimilars comprise biologics and biosimilar drugs taken orally for the targeted treatment of Alzheimer’s, multiple sclerosis, HIV or AIDS, and other serious conditions and are used to treat chronic diseases such as diabetes, arthritis, and cancer.

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