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How Has the Paget Disease Treatment Market Size Changed, over the years?

The market size for treating Paget’s disease has consistently expanded over recent years. It’s predicted to increase from $2.12 billion in 2024 to $2.21 billion in 2025, representing a compound annual growth rate (CAGR) of 4.1%. The progress during the historical period is owing to several factors, such as a hike in Paget’s disease incidence, heightened awareness, and diagnostic rates. Other contributing elements include the rise in aging population, enhancements in healthcare infrastructure, and increased uptake of bisphosphonates.

How Much Will the Paget Disease Treatment Market Be Worth in 2029?

The market for Paget’s disease is anticipated to witness steady expansion in the coming years, expected to reach $2.57 billion by 2029 with a compound annual growth rate (CAGR) of 3.9%. Factors contributing to this growth for the predicted period include the escalating demand for specific treatments, augmented health care spending, an increasing aging populace, the growth of clinical trials exploring new treatments, and an enhanced focus on customised medication. Key trends projected within this period encompass progress in therapy options, inclination towards biologic treatments, the advent of combo therapies, incorporation of digital health solutions and improvements in diagnostic technologies.

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Which is the Largest Company in the Paget Disease Treatment Market?

Major companies operating in the paget disease treatment market are Pfizer Inc., Merck & Co. Inc., AbbVie Inc., Novartis AG, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Teva Pharmaceutical Industries Ltd., Mylan N.V., Fresenius Kabi AG, Zimmer Biomet Holdings Inc., Eisai Co. Ltd., Sun Pharmaceutical Industries Limited, Apotex Inc., Sumitomo Pharma Co. Ltd., Aurobindo Pharma Limited, Dr. Reddy’s Laboratories Ltd., Cipla Limited, Endo International plc, Zaklady Farmaceutyczne Polpharma S.A., Abiogen Pharma S.p.A.

What Are the Main Market Drivers in the Paget Disease Treatment Industry?

The surge in cases related to arthritis and bone injuries is anticipated to fuel the expansion of the paget disease treatment market well into the future. Arthritis causes inflammation in the joints, while bone injuries might play a role in its onset. The spike in arthritis and bone injuries are linked to insufficient physical activity, which can weaken muscles and joints, limiting their capacity to provide mobility support and absorb impact. This leads to an increased likelihood of joint deterioration, rigidity, and fractures over time. Paget disease treatments aim at managing arthritis and bone injuries by mitigating bone aches, enhancing joint operation, and averting complications like fractures and distortions arising from irregular bone remodeling. As per The Centers for Disease Control and Prevention (CDC), a US-based national public health institute, in February 2024, in 2022, the age-adjusted prevalence of diagnosed arthritis in adults aged 18 and above was 18.9%, with a higher prevalence in women (21.5%) compared to men (16.1%). The incidence of arthritis escalated with age, varying from 3.6% in individuals aged between 18–34 to 53.9% in those aged 75 and above. Consequently, the augmentation in the number of cases linked to arthritis and bone injuries is the main driving force behind the growth of the paget disease treatment market.

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How Is the Paget Disease Treatment Market Segments Structured?

The paget disease treatment market covered in this report is segmented –

1) By Treatment Type: Actonel, Reclast, Zoledronic Acid, Fosamax, Miacalcin, Aredia, Calcitonin, Zometa, Other Treatments

2) By Route Of Administration: Oral, Intravenous, Topical

3) By Distribution Channels: Hospital Pharmacies, Retail Pharmacies, Online Pharmacie, Drug stores

4) By End User: Hospitals, Clinics, Other End-Users

Subsegmentss:

1) By Actonel: Risedronate Sodium Tablets, Delayed-Release Risedronate.

2) By Reclast: Intravenous Reclast, Annual Reclast Infusion.

3) By Zoledronic Acid: Zoledronic Acid 5 mg Injection, Zoledronic Acid 4 mg Injection.

4) By Fosamax: Alendronate Sodium Tablets, Alendronate Oral Solution

5) By Miacalcin: Miacalcin Nasal Spray, Miacalcin Injection

6) By Aredia: Pamidronate Disodium 30 mg Injection, Pamidronate Disodium 90 mg Injection

7) By Calcitonin: Synthetic Salmon Calcitonin, Human Calcitonin

8) By Zometa: Zometa 4 mg/5 mL Concentrate, Zometa 4 mg Infusion

9) By Other Treatments: Pain Management Medications, Physical Therapy, Surgical Interventions

What Strategic Trends Are Transforming the Paget Disease Treatment Market?

Major companies conducting business in the Paget disease treatment market are concentrating on the development of innovative products, such as calcium regulators, to increase treatment efficiency, improve patient results, and broaden their market footprint. A calcium regulator is a drug or substance that helps manage calcium levels in the blood and bones, creating a balance to support diverse physiological functions. For instance, Fresenius Kabi AG, a healthcare firm based in Germany, introduced a calcium regulator known as Calcitonin Salmon Injection, USP Synthetic in February 2025. This treatment was designed to control symptomatic Paget’s disease of the bone, hypercalcemia, and postmenopausal osteoporosis. This introduction aims to provide a more financially viable treatment choice, enhance their supply chain, and increase their collection of generic injectables. Fresenius Kabi has significantly invested in its facilities, aiming to ensure a consistent supply of necessary medicines, with the goal of improving patient care and becoming a key healthcare provider.

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Which Global Regions Offer the Highest Growth in the Paget Disease Treatment Market?

North America was the largest region in the paget disease treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the paget disease treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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This Report Delivers Insight On:

1. How big is the paget disease treatment market, and how is it changing globally?

2. Who are the major companies in the paget disease treatment market, and how are they performing?

3. What are the key opportunities and risks in the paget disease treatment market right now?

4. Which products or customer segments are growing the most in the paget disease treatment market?

5. What factors are helping or slowing down the growth of the paget disease treatment market?

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