How Will the PEGylated Proteins Market Grow? Key Trends and Opportunities for 2025 and Beyond
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What fueled the previous growth in the pegylated proteins market?
The market size for pegylated proteins has expanded quickly in the last few years. It is forecasted to rise from $1.47 billion in 2024 to $1.68 billion in 2025, with a compound annual growth rate (CAGR) of 14.1%. The expansion witnessed during the historic period is due to factors such as enhanced therapeutic effectiveness, an increasing aged population, the demand for sustained-release formulations, improved drug safety measures, and a wider range of applications, including targeted drug delivery systems.
What will be the pegylated proteins market size in the future?
Expectations for the pegylated proteins market size point towards brisk escalation in the upcoming years, projecting a value of $2.8 billion by 2029, yielding a compound annual growth rate (CAGR) of 13.7%. This significant expansion during the anticipated period can be tied to factors such as growing investment in treatments for rare ailments, the fast-paced evolution of the biopharmaceutical sector, the customization of precision medicine, a rise in competition with biosimilar versions of biologic drugs, and the procurement of inventive market access techniques. Foreseen trends for this period encompass digital health technologies integration, advancements in pegylation technologies, precision-driven and personalized formulations, emphasis on combination therapies, and a transition towards healthcare models that prioritize patient needs.
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What main drivers are fueling expansion in the pegylated proteins market?
The rise in lifestyle diseases is anticipated to boost the expansion of the PEGylated proteins market. Lifestyle diseases are health problems mainly attributable to unhealthy behaviors and lifestyle decisions, such as a poor diet, physical inactivity, and smoking. The prevalence of such diseases is increasing due to factors like less physical exercise, diets rich in processed foods, and heightened stress. PEGylated proteins play a key role in dealing with these diseases by improving the effectiveness, lasting capacity, and targeted delivery of therapeutic medications for disorders like cardiovascular diseases, diabetes, and certain types of cancer. For example, as per the Office for Health Improvement and Disparities, a government agency based in the UK, there was a slight upsurge from 63.8% in 2021 to 2022 to 64.0% in 2022 to 2023 with regard to the number of overweight adults or those living with obesity aged 18 and above in England. Thus, the growing predominance of lifestyle diseases is propelling the PEGylated proteins market’s growth.
What key areas define the segmentation of the global pegylated proteins market?
The pegylated proteins market covered in this report is segmented –
1) By Product: Consumable And Services, PEGylation Kits And Reagents, Monofunctional Linear PEGs, Bifunctional PEGs, Services, Other Products
2) By Protein Type: Colony Stimulating Factors, Interferons, Erythropoietin, Recombinant Factor VII, Other Protein Types
3) By Application: Cancer Treatment, Hepatitis, Chronic Kidney Diseases, Hemophilia, Multiple Sclerosis, Gastrointestinal Disorders, Other Applications
4) By End User: Pharmaceuticals, Biotechnology Companies, Contract Research Organizations, Academic Research Institutes
Subsegments:
1) By Consumable And Services: Consumables, Services (Contract Services, PEGylation Services)
2) By PEGylation Kits And Reagents: PEGylation Kits, Reagents
3) By Monofunctional Linear PEGs: Monofunctional PEGs For Protein Modification
4) By Bifunctional PEGs: Bifunctional PEGs For Protein Modification
5) By Other Products: Conjugates, PEGylated Drugs And Therapeutics
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Who are the dominant players expanding their reach in the pegylated proteins market?
Major companies operating in the PEGylated proteins market are Merck & Co. Inc., Bayer AG, Bristol Myers Squibb Company, AstraZeneca PLC, Roche Holding AG, Gilead Sciences Inc., Novo Nordisk A/S, Evonik Industries AG, Viatris Inc., Regeneron Pharmaceuticals Inc., Biogen Inc., Vertex Pharmaceuticals Incorporated, Lonza Group Ltd., Jazz Pharmaceuticals plc, Ipsen Pharma, Kyowa Kirin Co. Ltd., WuXi Biologics, BioMarin Pharmaceutical Inc., Ligand Pharmaceuticals Incorporated, Zydus Cadila, Enzon Pharmaceuticals Inc.
What emerging trends are influencing the growth of the pegylated proteins market?
Key players in the PEGylated protein market are striving to gain market advantage by creating novel items such as PEGylation reagents. These reagents are chemicals that bind polyethylene glycol (PEG) strands to biomolecules, modifying their properties for various biomedical uses. Creative Enzymes, a US-based company specializing in food additives and enzymes, unveiled DSPE-PEG-Maleimide for focused drug delivery in May 2023, as a case in point. DSPE-PEG-Maleimide (DSPE-PEG-MAL) is a distinctive heterobifunctional PEGylation reagent possessing DSPE phospholipids and maleimide. This versatile self-assembly agent can be utilized to produce PEGylated liposomes or micelles and it also offers thiol or cysteine reactive maleimide groups, being frequently used in targeted drug delivery.
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Which regions are emerging as leaders in the pegylated proteins market?
North America was the largest region in the PEGylated Proteins market in 2024. The regions covered in the PEGylated proteins market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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