How Is The Plasmid DNA Manufacturing Market Expected To Grow Through 2024-2033
The Business Research Company’s global market reports are now updated with the latest market sizing information for the year 2024 and forecasted to 2033
According to The Business Research Company’s Plasmid DNA Manufacturing Global Market Report 2024, the plasmid DNA manufacturing market is expected to show promising growth in the forecast period.
Exponential Growth in Recent Years
- Market Size Increase: The plasmid DNA manufacturing market has experienced significant growth, increasing from $1.89 billion in 2023 to $2.34 billion in 2024, marking a compound annual growth rate (CAGR) of 23.6%.
- Key Drivers: Factors contributing to this growth include:
- Application in industrial processes.
- Use in genetically modified organisms.
- Production of monoclonal antibodies.
- International health initiatives.
- Environmental applications like bioremediation.
- Microbiome studies.
Future Growth Projections
- Continued Expansion: The market is projected to grow to $5.49 billion by 2028, with a CAGR of 23.7%.
- Drivers of Future Growth:
- Development of DNA vaccines for infectious diseases.
- Adoption in antibody-drug conjugates and personalized therapies.
- Use in cancer treatments.
- Advancements in intellectual property.
Trends Shaping the Market
- Licensing Agreements: Increased activity in licensing agreements for plasmid DNA technologies.
- Customized Solutions: Development of tailored solutions to meet specific needs.
- Cost Reduction: Implementation of strategies to lower production costs.
- High-Throughput Screening: Adoption of high-throughput screening methods.
- Scalable Manufacturing: Creation of scalable manufacturing solutions.
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Gene Therapy Driving Market Growth
- Gene Therapy Boom: Growing acceptance of gene therapy, which modifies genes to treat or prevent diseases, is a significant market driver.
- Advancements: Improvements in genetic engineering technologies and increased R&D investment.
- Clinical Trials: Successful clinical trials and the rise in genetic disorders highlight the potential of gene therapy for long-term cures.
- Plasmid DNA’s Role: Essential in producing vectors for gene therapy, facilitating genetic disorder treatments.
- Clinical Trials Data: According to the American Society of Gene & Cell Therapy, the number of gene therapies in Phase III trials increased by 10% in Q3 2023.
Leading Companies in the Market
- Major Players: Key companies include Thermo Fisher Scientific Inc., Eurofins Genomics LLC, Catalent Inc., Charles River Laboratories, and Recipharm AB.
- Other Notable Firms: Genscript Biotech Corporation, Aldevron LLC, Genewiz, OriGene Technologies, and Celonic AG.
Innovations in Plasmid DNA Production
- Advanced Bioprocessing Technologies: Companies are developing technologies to enhance efficiency, scalability, and quality.
- Example: In January 2023, Charles River Laboratories launched the eXpDNA platform, integrating advanced technologies for high-quality plasmid DNA production.
- Applications: Used in gene therapy, DNA vaccine development, and other biopharmaceutical applications requiring high yield, purity, and consistency.
Strategic Acquisitions
- Danaher Corporation and Aldevron: In August 2021, Danaher Corporation acquired Aldevron for $9.6 billion.
- Impact: This acquisition enhances Danaher’s biotech capabilities, supporting the development of genetic treatments and advancing biotech research.
Market Segmentation
- By Grade:
- Research and Development Grade
- Good Manufacturing Practice (GMP) Grade
- By Development Phase:
- Pre-Clinical Therapeutics
- Clinical Therapeutics
- Marketed Therapeutics
- By Disease:
- Infectious Disease
- Cancer
- Genetic Disorder
- Other Diseases
- By Application:
- DNA Vaccines
- Cell and Gene Therapy
- Immunotherapy
- Other Applications
Regional Insights
- North America: Largest market in 2023.
- Asia-Pacific: Expected to be the fastest-growing region during the forecast period.
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