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What key factors are powering the surge in the plasmid dna manufacturing market right now?

The market size for plasmid DNA manufacturing has seen an exponential upsurge in the recent past. The projected growth is from $2.34 billion in 2024 to $2.9 billion in 2025, indicating a compound annual growth rate (CAGR) of 23.9%. The significant growth over the historic period can be credited to different factors such as industrial applications of plasmid DNA, its use in engineering genetically modified organisms, generation of monoclonal antibodies via plasmid DNA in cell lines, global health campaigns, use of plasmid DNA in bioremediation and other environmental uses, along with microbiome research.

How fast Is the plasmid dna manufacturing market expected to grow, and what’s its future value?

The market size for plasmid DNA manufacturing is predicted to experience significant expansion in the coming years, with a projected valuation of $6.78 billion by 2029 and a compound annual growth rate (CAGR) of 23.6%. This projected growth during the forecast period can be linked to the rising applications of plasmid DNA, such as in the creation of DNA vaccines for infectious diseases, the rise in use in the creation of antibody-drug conjugates, personalized therapeutics, and cancer treatments, as well as advancements in intellectual property. Key trends expected to arise during the forecast period comprise increased engagement in licensing agreements related to plasmid DNA technology, tailored solutions, strategies for lowering costs, high-capacity screening, and the creation of versatile manufacturing solutions.

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What are the leading drivers of growth in the plasmid dna manufacturing market?

The plasmid DNA manufacturing market is predicted to expand, propelled by the escalating acceptance of gene therapy. This medical procedure, which amends or manipulates an individual’s genes to cure or prevent illnesses, is seeing an upswing. This upward trend is largely due to enhancements in genetic engineering technologies, increased investments in research and development, the success of clinical trials, and a rising prevalence of genetic conditions. These factors underscore the promising ability of gene therapy to provide enduring or even permanent remedies. In the process of gene therapy, plasmid DNA manufacturing is vital as it generates the vectors necessary for therapeutic genes’ transmission into cells, thus aiding in the treatment of genetic disorders. For example, the American Society of Gene & Cell Therapy, a non-profit medical and scientific organization based in the US, reports a 10% growth in Phase III clinical trials of gene therapies in Q3 2023, marking the first quarterly growth since Q3 2022. Consequently, the increasing endorsement of gene therapy is fostering the growth of the plasmid DNA manufacturing market.

What are the key segments defining the plasmid dna manufacturing market?

The plasmid DNA manufacturing market covered in this report is segmented –

1) By Grade: Research And Development Grade, Good Manufacturing Practice (GMP) Grade

2) By Development Phase: Pre-Clinical Therapeutics, Clinical Therapeutics, Marketed Therapeutics

3) By Disease: Infectious Disease, Cancer, Genetic Disorder, Other Diseases

4) By Application: Deoxyribonucleic Acid (DNA) Vaccines, Cell And Gene Therapy, Immunotherapy, Other Applications

Subsegments:

1) By Research And Development Grade: Small-scale Plasmid DNA Production, Preclinical Research Plasmid DNA

2) By Good Manufacturing Practice (GMP) Grade: Clinical Trial Material Production, Commercial-Scale Plasmid DNA Production

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Who are the key players steering the development of the plasmid dna manufacturing market?

Major companies operating in the plasmid DNA manufacturing market are Thermo Fisher Scientific Inc., Eurofins Genomics LLC, Catalent Inc., Charles River Laboratories, Recipharm AB, Kaneka Corp., Genscript Biotech Corporation, Aldevron LLC, Genewiz, OriGene Technologies, Celonic AG, Creative Biogene, Cellectis, Synbio Technologies, VectorBuilder Inc., Altogen Biosystems, Addgene, Andelyn Biosciences, AGC Biologics, VGXI, BioCat GmbH, GeneCopoeia, PlasmidFactory GmbH & Co. KG, Akron Biotech, PackGene Biotech lnc.

What are the key trends shaping the future of the plasmid dna manufacturing market?

Leading businesses in the plasmid DNA manufacturing market are exploiting progressive bioprocessing technologies to amplify the effectiveness, scalability, and quality of plasmid DNA manufacture. These advancements are designed to expedite the manufacturing procedure, decrease production expenses, and certify that the plasmid DNA adheres to strict regulatory criteria for therapeutic applications. For example, Charles River Laboratories, a pharmaceutical enterprise from the US, unveiled its eXpDNA platform in January 2023. This platform, which is fashioned specifically for the efficient creation and purifying of top-grade plasmid DNA, unifies progressive bioprocessing technologies, scalable manufacturing techniques, and strict quality control exercises. It’s employed significantly in gene therapy, DNA vaccine advancement, and other biopharmaceutical applications that necessitate high output, purity, and consistency.

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Which regions are most influential in expanding the plasmid dna manufacturing market?

North America was the largest region in the plasmid DNA manufacturing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the plasmid DNA manufacturing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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