2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

How Are Key Drivers Contributing to the Growth and Expansion of the Plasmid DNA Manufacturing Market?

The growing acceptance of gene therapy is expected to drive the expansion of the plasmid DNA manufacturing market. Gene therapy involves modifying a person’s genes to treat or prevent diseases. Advancements in genetic engineering, increasing research investment, successful trials, and the rise in genetic disorders all point to the potential for long-term cures. Plasmid DNA manufacturing is crucial for gene therapy, as it produces the vectors needed to deliver therapeutic genes. For example, the American Society of Gene & Cell Therapy reported a 10% increase in gene therapies in Phase III trials in Q3 2023, the first quarterly rise since Q3 2022. Therefore, the growing acceptance of gene therapy is fueling the growth of the plasmid DNA manufacturing market.

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How Will the Growth Rate of thePlasmid DNA Manufacturing Market Impact Industry Trends by 2034?

The plasmid DNA manufacturing market size expanded significantly, rising from $2.34 billion in 2024 to $2.9 billion in 2025 at a CAGR of 23.9%, due to its role in GMOs, antibody production, environmental uses, health initiatives, and microbiome studies.

The plasmid DNA manufacturing market is projected to experience exponential growth, reaching $6.78 billion in 2029 at a CAGR of 23.6%. The growth is attributed to the use of plasmid DNA in DNA vaccines, antibody-drug conjugates, personalized therapies, cancer treatments, and intellectual property developments. Key trends include licensing agreements, customized solutions, cost reduction, high-throughput screening, and scalable manufacturing development.

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What New Market Trends Are Reshaping thePlasmid DNA Manufacturing Market and Its Opportunities?

Companies in the plasmid DNA manufacturing market are enhancing bioprocessing technologies to improve production efficiency and quality. These innovations streamline manufacturing, reduce costs, and meet strict regulatory standards. For example, in January 2023, Charles River Laboratories, a US-based pharmaceutical company, launched the eXpDNA platform for efficient plasmid DNA production. This platform integrates advanced technologies, scalable production methods, and strict quality control measures to produce high-quality plasmid DNA for therapeutic and clinical applications.

Who Are the Leading Market Players Fueling Growth in the Plasmid DNA Manufacturing Market Trend?

Major companies operating in the plasmid DNA manufacturing market are Thermo Fisher Scientific Inc., Eurofins Genomics LLC, Catalent Inc., Charles River Laboratories, Recipharm AB, Kaneka Corp., Genscript Biotech Corporation, Aldevron LLC, Genewiz, OriGene Technologies, Celonic AG, Creative Biogene, Cellectis, Synbio Technologies, VectorBuilder Inc., Altogen Biosystems, Addgene, Andelyn Biosciences, AGC Biologics, VGXI, BioCat GmbH, GeneCopoeia, PlasmidFactory GmbH & Co. KG, Akron Biotech, PackGene Biotech lnc.

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How is the Global Plasmid DNA Manufacturing Market Segemented?

The plasmid DNA manufacturing market covered in this report is segmented –

1) By Grade: Research And Development Grade, Good Manufacturing Practice (GMP) Grade

2) By Development Phase: Pre-Clinical Therapeutics, Clinical Therapeutics, Marketed Therapeutics

3) By Disease: Infectious Disease, Cancer, Genetic Disorder, Other Diseases

4) By Application: Deoxyribonucleic Acid (DNA) Vaccines, Cell And Gene Therapy, Immunotherapy, Other Applications

Subsegments:

1) By Research And Development Grade: Small-scale Plasmid DNA Production, Preclinical Research Plasmid DNA

2) By Good Manufacturing Practice (GMP) Grade: Clinical Trial Material Production, Commercial-Scale Plasmid DNA Production

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Which Geographics are Influencing the Growth of the Plasmid DNA Manufacturing Market?

North America was the largest region in the plasmid DNA manufacturing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the plasmid DNA manufacturing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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