Future Outlook of the Pruritus Therapeutics Market: Growth, Trends, and Emerging Opportunities Explored
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What fueled the previous growth in the pruritus therapeutics market?
The market for pruritus therapeutics has experienced robust growth in recent years, expanding from a value of $11.89 billion in 2024 to an estimated $12.51 billion in 2025. This represents a compound annual growth rate (CAGR) of 5.3%. Several factors have contributed to this growth in the historic period, including an increase in cases of pruritus, a variety of causes and conditions, a rising elderly population, and a focus on improving the quality of life for patients.
What will be the pruritus therapeutics market size in the future?
The market for pruritus therapies is anticipated to experience substantial growth in the upcoming years, projected to reach a value of $16.05 billion in 2029 with a Compound Annual Growth Rate (CAGR) of 6.4%. The expansion during the forecast period can be credited to the broadening understanding of pruritus pathophysiology, the invention of novel drug formulations and delivery methodologies, concentration on bespoke medicine, an escalation in dermatological research and development, improved awareness and diagnosis rates, and an increasing inclination towards botanical and herbal treatments. Leading trends for the forecast period encompass the creation of itch-specific receptor agonists and antagonists, market prioritization on personalized therapeutic strategies, incorporation of technology in itch supervision and control, and partnerships for interdisciplinary research.
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What main drivers are fueling expansion in the pruritus therapeutics market?
The escalation in the prevalence of skin-related conditions is anticipated to stimulate the growth of the pruritus therapeutics market. These dermatological conditions encompass disorders related to skin, hair, nails, and mucous membranes, extending from acne and eczema to skin cancer and fungal infections. The primary source of itchiness generally dictates the use of pruritus treatments for these skin diseases. The treatments involve topical applications, creams and moisturizers, immunosuppressive drugs, and anti-itching medications. For instance, in January 2024, data from the American Cancer Society, a non-profit organization in the US aimed at eradicating cancer, predicts 108,270 reported cases of skin cancer, marking a 3.2% increase from the 104,930 cases logged in 2023. Consequently, the surge in skin-related disorders is spurring the growth of the pruritus therapeutics market.
What key areas define the segmentation of the global pruritus therapeutics market?
The pruritus therapeutics market covered in this report is segmented –
1) By Product: Corticosteroids, Antihistamines, Local Anesthetics, Counterirritants, Immunosuppressants, Calcineurin Inhibitors, Other Products
2) By Route Of Administration: Oral, Parenteral, Topical
3) By Disease Type: Atopic Dermatitis, Allergic Contact Dermatitis, Urticaria, Cutaneous T-Cell, Other Disease Types
4) By End-User: Hospitals, Clinics, Other End Users
Subsegments:
1) By Corticosteroids: Topical Corticosteroids, Systemic Corticosteroids
2) By Antihistamines: First-Generation Antihistamines, Second-Generation Antihistamines
3) By Local Anesthetics: Topical Local Anesthetics
4) By Counterirritants: Menthol-Based Products, Camphor-Based Products
5) By Immunosuppressants: Topical Immunosuppressants, Systemic Immunosuppressants
6) By Calcineurin Inhibitors: Tacrolimus Ointment, Pimecrolimus Cream
7) By Other Products: Moisturizers And Emollients, Antipruritic Herbal Remedies, Combination Therapies
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Who are the dominant players expanding their reach in the pruritus therapeutics market?
Major companies operating in the pruritus therapeutics market include Pfizer Inc., Johnson & Johnson, AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb Company, Eli Lilly and Company, Regeneron Pharmaceuticals Inc., Astellas Pharma Inc. , Bausch Health Companies Inc., Galderma Laboratories LP, Cipla Limited, LEO Pharma AS, Cara Therapeutics Inc., GlaxoSmithKline Plc, Novan Inc., Escient Pharmaceuticals Inc., Nerre Therapeutic Ltd., EPI Health LLC, Trevi Therapeutics Inc., Evelo Biosciences, Toray Medical Co. Ltd.
How are evolving market trends shaping pruritus therapeutics Strategies?
Prominent players in the pruritus therapeutics market are concentrating their efforts on the creation of specialized treatments for unique diseases and specific demographic groups, such as a non-systemic ileal bile acid transport inhibitor, an avenue of personalized medicine aiming to fulfill unmet medical requirements. This type of medication targets bile acid absorption in the intestine without substantially affecting systemic circulation, hence reducing potential side effects. For example, Ipsen, a pharmaceutical company located in France, obtained approval from the Food and Drug Administration (FDA), a federal agency from the United States Department of Health and Human Services, for their drug Bylvay (odevixibat) in June 2023. This drug is aimed at treating cholestatic pruritus in patients aged 12 months and older who have Alagille syndrome (ALGS). Bylvay is a daily, non-systemic ileal bile acid transport inhibitor (IBATi) that has minimal systemic exposure and is the first of its kind to be approved in the U.S for cholestatic pruritus due to progressive familial intrahepatic cholestasis (PFIC). It was previously sanctioned for PFIC treatment in Europe and is now accessible through prescription for qualifying ALGS patients.
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Which regions are emerging as leaders in the pruritus therapeutics market?
North America was the largest region in the pruritus treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the pruritus therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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