Medical Equipment

What’s Driving Growth in the Tangential Flow Filtration Market? Insights into Key Trends and Opportunities

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What key factors are powering the surge in the tangential flow filtration market right now?

The market size for tangential flow filtration has experienced considerable growth in the past few years. The forecast suggests it will expand from $1.41 billion in 2024 to $1.58 billion in 2025, showing a compound annual growth rate (CAGR) of 12.1%. Factors contributing to this growth during the historical period include the development of the biopharmaceutical industry, an increase in cell and gene therapy manufacturing, regulatory compliance, worldwide economic condition, healthcare expenditure, the rising use in vaccine production, and an emphasis on drug safety and purity.

How fast Is the tangential flow filtration market expected to grow, and what’s its future value?

The market for tangential flow filtration is set to witness a swift expansion in the forthcoming years, ballooning to a size of $2.74 billion by 2029 and registering a compound annual growth rate (CAGR) of 14.8%. This projected growth over the forecast period is linked to several factors such as the arrival of mRNA vaccine production, the rising use in exosome purification, the proliferation of cell culture-based production, an emphasis on scalability and adaptability, improvements in membrane chemistry, and an uptick in its application in nanoparticle separation. Other key trends shaping the forecast period include concerted research and development efforts, the implementation of single-use systems, the application of cutting-edge membrane technologies, the use of high throughput screening, and advancements in gene and cell therapy, bioprocess intensification, technological integration, and the role of contract manufacturing organizations (CMOs).

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What are the leading drivers of growth in the tangential flow filtration market?

The tangential flow filtration market is anticipated to expand owing to the escalation in research and development (R&D) expenditures in the pharmaceutical and biotechnology sectors. Tangential flow filtration (TFF), often used in the downstream processing of biopharmaceutical products for concentration and processing, will benefit considerably from this increase in R&D investment. In line with reports from the UK’s GOV.UK, a government department, it was revealed that in 2022, £9.0 billion ($11.7 billion), or 0.36% of the UK’s GDP, was spent on pharmaceutical R&D activities by the business enterprise sector. This constituted 18% of the total R&D undertaken by UK businesses, the highest proportion across all product areas. Consequently, it is projected that the rising R&D spending will stimulate the demand for the tangential flow filtration market during the forecast period.

What are the key segments defining the tangential flow filtration market?

The tangential flow filtration market covered in this report is segmented –

1) By Product: Reusable Systems, Single-Use Systems, Membrane Filters

2) By Technology: Ultrafiltration, Microfiltration, Reverse Osmosis

3) By Application: Bioprocess Applications, Viral Vector, Vaccine Purification, Other Applications

Subsegments:

1) By Reusable Systems: Crossflow Filtration Systems, Automated Tangential Flow Systems, Batch Systems

2) By Single-Use Systems: Pre-sterilized Single-Use Assemblies, Disposable Filter Capsules, Single-Use Bioreactors

3) By Membrane Filters: Ultrafiltration Membranes, Microfiltration Membranes, Nanofiltration Membranes, Reverse Osmosis Membranes

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Who are the key players steering the development of the tangential flow filtration market?

Major companies operating in the tangential flow filtration market are Danaher Corporation, Koch Membrane Systems Inc., Merck Millipore, Sartorius AG, GE Healthcare, Parker Hannifin Corporation, Repligen Corporation, Alfa Laval Corporate AB, Andritz AG, Sterlitech Corporation, Meissner Filtration Products Inc., Spectrum Inc., TangenX Technology Corporation, Watersep Bioseparations Corporation, Pall Corporation, Novasep Holding SAS, Asahi Kasei Corporation, Graver Technologies, GEA Group Aktiengesellschaft, Filtration Group Corporation, 3M Company, Amazon Filters Ltd., Advantec MFS Inc., Membrane Solutions LLC, Entegris Inc.

What emerging trends are influencing the growth of the tangential flow filtration market?

Top firms in the tangential flow filtration market are concentrating on the development of novel solutions like tangential flow filtration cassettes specifically designed for laboratories, aiming to improve the efficiency and accuracy in bioprocessing applications. The term “laboratory-focused tangential flow filtration cassettes” refers to unique devices designed for the tangential flow filtration (TFF) process in laboratories. In September 2024, for example, Sartorius AG, a pharmaceutical and laboratory equipment supplier based in Germany, launched the Vivaflow SU, a new generation tangential flow filtration (TFF) cassette. This TFF equipment is designed to deal with feed volumes varying from 100 mL to 1,000 mL and is formulated for utilization in ultrafiltration and diafiltration methodologies. This user-friendly cassette makes the setup process simple, negating the need for complex settings with its readiness to integrate with frequently used laboratory pumps. The design considers environmental factors and employs eco-sensitive materials, using 30.5% less plastic than its predecessor models, thereby reducing its ecological footprint.

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Which regions are most influential in expanding the tangential flow filtration market?

North America was the largest region in the tangential flow filtration market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the tangential flow filtration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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