Therapeutic Plasma Exchange Market Insights 2025-2034: Growth Dynamics, Trends, and Strategic Opportunities
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How has the therapeutic plasma exchange market grown in recent years?
In the past few years, the market size of therapeutic plasma exchange has increased significantly. It is anticipated to rise from $1.47 billion in 2024 to $1.62 billion in 2025, with a compound annual growth rate (CAGR) of 9.8%. The growth during this historical period is due to the rising incidence of immune disorders, advancements in technology, heightened awareness and education, proliferation of indications, and a greater comprehension of pathophysiology.
How is the therapeutic plasma exchange market size expected to evolve during the forecast period?
The therapeutic plasma exchange market size is expected to see strong growth in the next few years. It will grow to $2.32 billion in 2029 at a compound annual growth rate (CAGR) of 9.5%. The growth in the forecast period can be attributed to the rising geriatric population, clinical evidence and guidelines, regulatory environment, hospital infrastructure and healthcare investments, healthcare expenditure, and reimbursement policies. Major trends in the forecast period include personalized therapies, integration of automation, collaborative initiatives, and telemedicine integration.
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Which key drivers are propelling the therapeutic plasma exchange market’s growth?
The therapeutic plasma exchange market is predicted to see significant growth due to the increased prevalence of hematological disorders. These blood disorders are conditions that impact the blood and related tissues such as bone marrow, lymph nodes, and the spleen. Factors like genetic predispositions, environmental factors, and changes in lifestyle are contributing to the rise in hematological disorders. Therapeutic plasma exchange (TPE) is often used as a treatment method for these disorders, serving to eliminate harmful substances from the plasma, such as autoantibodies in autoimmune hemolytic anemia and immune complexes in thrombotic thrombocytopenic purpura, consequently alleviating the severity of the disease, thus improving patient prognosis. For example, in August 2023, the Leukemia and Lymphoma Society, a professional organization based in the US, predicts that the number of myeloma diagnoses will increase by approximately 2.3% from 2021 to 2023, rising from 34,920 cases to 35,730. As such, this surge in hematological disorders is fueling the expansion of the therapeutic plasma exchange market.
What are the market segments in the therapeutic plasma exchange industry?
The therapeutic plasma exchange market covered in this report is segmented –
1) By Type: Therapeutic Plasma Exchange (TPE), Double Filtered Plasmapheresis (DFPP)
2) By Indication: Neurological Disorders, Hematological Disorders, Renal Disorders, Metabolic Disorders, Other Indications
3) By Technology: Centrifugation, Membrane Separation
4) By End User: Blood Collection Centers, Hospitals And Clinics, Transfusion Centers, Other End Users
Subsegments:
1) By Therapeutic Plasma Exchange (Tpe): Manual Tpe, Automated Tpe
2) By Double Filtered Plasmapheresis (Dfpp): Single-Stage Dfpp, Multi-Stage Dfpp
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Who are the key players steering the development of the therapeutic plasma exchange market?
Major companies operating in the therapeutic plasma exchange market are Medica S.p.A., Fresenius SE and Co. KGaA, Medtronic Plc., Asahi Kasei Corporation, Toray Industries Inc., Baxter International Inc., B Braun Melsungen AG, Terumo Corporation, Kaneka Corporation, Charles River Laboratories, Octapharma AG, Spectral Medical Inc., Nikkiso Co. Ltd., Haemonetics Corporation, Miltenyi Biotec Technology And Trading Co. Ltd., Macopharma SA, Cerus Corporation, Apellis Pharmaceuticals Inc., ImmunoTek Bio Centers LLC, CytoSorbents Corporation, Kawasumi Laboratories America Inc., Japan Medical Supply Co. Ltd.
What key trends are currently impacting the therapeutic plasma exchange market’s development?
Major businesses in the therapeutic plasma exchange market are embracing strategies of forming partnerships to boost technology assimilation and amplify their market influence. These strategic partnerships are typically a cooperative alliance between two or more firms, pooling their resources, know-how, and efforts with the aim of accomplishing shared targets. For example, in July 2022, Terumo Blood and Cell Technologies, a technology firm based in the US, joined forces with Eliaz Therapeutics Inc., a US-based medical device firm that specializes in therapeutic apheresis for kidney-related and inflammatory ailments. This partnership is geared towards tackling acute kidney injury (AKI) and sepsis-induced AKI (S-AKI) by specifically eliminating the Gal-3 inflammatory protein from blood plasma. Given the high fatality ratio linked with AKI, the partnership seeks to investigate new remedies using Terumo’s Spectra Optia Apheresis System and ETI’s XGal-3 column. The initial studies will concentrate on large animals, advancing eventually to human clinical trials. Terumo, renowned for its inventive approaches in therapeutic apheresis, has previously cooperated on projects aimed at conditions like triple-negative breast cancer and COVID-19.
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Which regions are most influential in expanding the therapeutic plasma exchange market?
North America was the largest region in the therapeutic plasma exchange market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the therapeutic plasma exchange market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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