Discover trends, market shifts, and competitive outlooks for the therapeutic plasma exchange industry through 2025-2034 with The Business Research Company’s reliable data and in-depth research

What Are the Key Milestones in the Therapeutic Plasma Exchange Market’s Growth Trajectory From 2025 To 2034?

The market size for therapeutic plasma exchange has seen robust growth in the past few years. This market is projected to grow from $1.47 billion in 2024 to $1.62 billion in 2025, with a compound annual growth rate (CAGR) of 9.8%. The growth seen in the historical period can be traced back to the rise of immunological diseases, the advancement in technology, enhanced awareness and education, widened indications, and a more refined comprehension of the pathophysiology.

The market size for therapeutic plasma exchange is projected to experience robust growth in the coming years, anticipated to reach $2.32 billion by 2029, with a compound annual growth rate (CAGR) of 9.5%. The growth during the forecast period could be a result of a growing geriatric population, clinical proof and guidelines, regulatory landscape, developments in hospital infrastructure and healthcare investments, healthcare spending, and reimbursement policies. The forecast period is also likely to witness significant trends such as personalized therapies, automation integration, collaborative efforts, and the inclusion of telemedicine.

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Which Factors and External Forces Are Driving Demand in the Therapeutic Plasma Exchange Market?

The therapeutic plasma exchange market is poised for growth, largely driven by the increasing incidence of hematological disorders. Hematological disorders or blood disorders involve health issues that affect the blood and the tissues involved in blood formation such as the bone marrow, lymph nodes, and spleen. Various factors such as genetic predispositions, environmental factors, and lifestyle changes contribute to their rise. Therapeutic plasma exchange (TPE) plays a pivotal role in treating hematological disorders by eliminating harmful substances like autoantibodies in autoimmune hemolytic anemia or immune complexes in thrombotic thrombocytopenic purpura from the plasma, thus reducing the severity of the disease and enhancing patient outcomes. For instance, the Leukemia and Lymphoma Society, based in the US, predicted in August 2023 that the number of anticipated myeloma diagnoses will grow by roughly 2.3% from 2021 to 2023, moving from 34,920 to 35,730. Hence, the increasing prevalence of hematological disorders is fuelling the expansion of the therapeutic plasma exchange market.

How Is the Therapeutic Plasma Exchange Market Segmented?

The therapeutic plasma exchange market covered in this report is segmented –

1) By Type: Therapeutic Plasma Exchange (TPE), Double Filtered Plasmapheresis (DFPP)

2) By Indication: Neurological Disorders, Hematological Disorders, Renal Disorders, Metabolic Disorders, Other Indications

3) By Technology: Centrifugation, Membrane Separation

4) By End User: Blood Collection Centers, Hospitals And Clinics, Transfusion Centers, Other End Users

Subsegments:

1) By Therapeutic Plasma Exchange (Tpe): Manual Tpe, Automated Tpe

2) By Double Filtered Plasmapheresis (Dfpp): Single-Stage Dfpp, Multi-Stage Dfpp

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What Are the Fastest-Growing Geographies in the Therapeutic Plasma Exchange Market?

North America was the largest region in the therapeutic plasma exchange market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the therapeutic plasma exchange market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Key Trends Are Shaping the Future of the Therapeutic Plasma Exchange Market?

Leading firms in the therapeutic plasma exchange market are leveraging strategic partnerships to increase technology integration and broaden their market influence. A strategic partnership is often a cooperative relationship between two or more firms that pool their resources, skills, and efforts to achieve shared aims or objectives. For example, in July 2022, Terumo Blood and Cell Technologies, a technology firm based in the US, joined forces with Eliaz Therapeutics Inc., an American medical device firm that specializes in therapeutic apheresis for inflammatory and kidney-related ailments. This partnership aims to address acute kidney injury (AKI) and sepsis-induced AKI (S-AKI) by selectively eliminating the Gal-3 inflammatory protein from blood plasma. Given the high mortality rates tied to AKI, the partnership’s goal is to investigate new treatments using Terumo’s Spectra Optia Apheresis System and ETI’s XGal-3 column. The initial research will center on large animals, followed by human clinical trials. Terumo, which is recognized for its innovative approach to therapeutic apheresis, has previously joined forces with others on projects aimed at conditions such as triple-negative breast cancer and COVID-19.

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How Is the Therapeutic Plasma Exchange Market Defined and What Are Its Core Parameters?

Therapeutic plasma exchange (TPE) refers to a medical procedure used to treat certain autoimmune diseases and other conditions. During TPE, blood is removed from the body, plasma (the liquid portion of the blood) is separated from the blood cells, and then the blood cells are returned to the body, often after being mixed with a replacement fluid. This process helps remove harmful substances from the blood, such as autoantibodies or toxins, which can contribute to various diseases.

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