Unlocking Opportunities in the Transthyretin Amyloidosis Treatment Market: Key Trends, Market Growth, and Forecast Insights
2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!
What Major Innovations Are Driving the Accelerated Growth of the Transthyretin Amyloidosis Treatment Market?
As the industry expands its financial commitments to scientific exploration and innovation, the transthyretin amyloidosis treatment market is anticipated to experience significant growth. These investments in research and development (R&D) are geared towards enhancing scientific understanding, designing breakthrough technologies, formulating innovative products, and refining existing procedures. Expanded investments into R&D pave the way for the discovery and development of novel treatment alternatives for transthyretin amyloidosis, such as new drugs, gene therapies, and precision medicine techniques. These advances provide patients with more efficient and personalised treatment solutions. For example, in December 2022, Alnylam Pharmaceuticals, a US-based biopharmaceutical firm committed to the development of Vutrisiran, a treatment for ATTR amyloidosis, raised its R&D investment by 11.49% to $883,015 in 2022 from $792,156 in 2021. Consequently, the escalating investment in research and development is fuelling the transthyretin amyloidosis treatment market’s expansion. Emerging Transthyretin Amyloidosis Treatment Market Driver: Increasing Senior Population Demographics Drive Expansion In Transthyretin Amyloidosis Treatment Market
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How Has the Transthyretin Amyloidosis Treatment Market Evolved in Recent Years, and What are the Growth Projections for the Forecast Period?
In recent times, there has been a robust increase in the size of the transthyretin amyloidosis treatment market. It is anticipated to escalate from $5.52 billion in 2024 to about $5.95 billion in 2025, showcasing a compound annual growth rate (CAGR) of 7.8%. This growth in the past period is due to a rise in awareness regarding the disease, the progression in diagnostic instruments, development and approval of drugs, patient advocacy and assistance, as well as collaboration in research.
The market for transthyretin amyloidosis treatments is projected to witness robust expansion in the coming years, escalating to $8.04 billion by 2029 with a 7.8% compound annual growth rate (CAGR). Factors contributing to this predicted surge during the forecast period involve a broadened therapeutic pipeline, enhanced genetic testing, worldwide initiatives to raise awareness about rare diseases, the application of personalized medicine, and improved treatment accessibility. Key trends anticipated during this period encompass the development of combination therapies, establishing strategic partnerships for drug advancement, concentration on targeting peripheral and cardiac symptoms, the execution of patient education programs, and the integration of real-world evidence into treatment protocols.
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What Are the Most Significant Market Trends Transforming theTransthyretin Amyloidosis Treatment Market?
Leading firms in the transthyretin amyloidosis treatment market are concentrating on devising inventive and specialised remedies, such as orphan drugs, to increase patient benefits and broaden the scope of treatments. Eplontersen, an orphan drug, is purposely created to address transthyretin amyloidosis, and often gains regulatory advantages for its development. For instance, in March 2023, Ionis Pharmaceuticals, Inc., a biotechnology research firm based in Canada, won FDA approval for a new drug application for Eplontersen, an experimental orphan drug designed to combat familial transthyretin-induced amyloid, which results in progressive polyneuropathy. Eplontersen’s goal is to decrease the production of transthyretin (TTR) protein and address both the inherited and non-inherited types of ATTR amyloidosis (amyloid transthyretin amyloidosis). In 2022, the FDA awarded Eplontersen the status of an orphan drug.
What Are the Top Market Players Propelling the Growth of theTransthyretin Amyloidosis Treatment Industry?
Major companies operating in the transthyretin amyloidosis treatment market report are Pfizer Inc., Abbvie Inc., Sanofi S.A., Bristol Myers Squibb Company, AstraZeneca PLC, GSK PLC, Novo Nordisk A/S, Merck & Co. Inc., Astellas Pharma Inc., Alexion Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., PTC Therapeutics, Ionis Pharmaceuticals, Prothena Corporation PLC, BridgeBio Pharma Inc., Sorrento Therapeutics Inc., Intellia Therapeutics, Akcea Therapeutics Inc., Eidos Therapeutics Inc., Acrotech Biopharma Inc., Spectrum Pharmaceuticals Inc., Neurimmune AG, BELLUS Health Inc., Corino Therapeutics Inc., Celgene Corp, SOM Innovation Biotech S.A
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Which Primary Segments of the Transthyretin Amyloidosis Treatment Market Are Driving Growth and Industry Transformations?
The transthyretin amyloidosis treatment market covered in this report is segmented –
1) By Type: Transthyretin Amyloidosis With Polyneuropathy (ATTR-PN), Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
2) By Drug: Tafamidis, Patisiran, Inotersen, Other Drugs
3) By Therapy: Targeted Therapy, Supportive Therapy, Pipeline Therapy
4) By Distribution Channel: Hospital Pharmacies, Specialty Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By Transthyretin Amyloidosis With Polyneuropathy (ATTR-PN): Early-Stage ATTR-PN, Advanced-Stage ATTR-PN
2) By Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM): Mild ATTR-CM, Moderate ATTR-CM, Severe ATTR-CM
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Which Regions Are Key Players in the Growth of the #What Major Innovations Are Driving the Accelerated Growth of the Transthyretin Amyloidosis Treatment Market?# Market?
North America was the largest region in the transthyretin amyloidosis treatment market in 2024. The regions covered in the transthyretin amyloidosis treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
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