2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What External and Internal Drivers Are Contributing to the Growth of theUpstream Bioprocessing Market?

The outsourcing of biopharmaceutical manufacturing is expected to drive the growth of the upstream bioprocessing market. This outsourcing involves delegating parts of the production process to external companies such as contract manufacturing organizations (CMOs) and contract development and manufacturing organizations (CDMOs). Key drivers include cost efficiency, specialized expertise, scalability, and risk reduction. Outsourcing enhances product development by streamlining operations and cutting costs. According to BDO USA, by 2025, CDMOs and hybrid manufacturing companies will manage 44% of the global mammalian capacity. Therefore, the outsourcing trend is propelling the growth of the upstream bioprocessing market.

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What is the Predicted Annual Growth Rate of theUpstream Bioprocessing Market Impact Industry Trends by 2034?

The upstream bioprocessing market size has grown rapidly in recent years. It will grow from $12.03 billion in 2024 to $13.66 billion in 2025, at a compound annual growth rate (CAGR) of 13.6%. The growth in the historic period is attributed to the need for process optimization, safe and efficient production of biomolecules, rising demand for biotherapeutics, implementation of process analytical technology, increased research into biosimilars, and the prevalence of chronic diseases.

The upstream bioprocessing market is projected to grow to $22.43 billion by 2029 at a CAGR of 13.2%. Growth drivers include the commercial use of single-use bioreactors, biopharmaceutical manufacturing outsourcing, the rapid growth of the pharmaceutical and biotechnology industries, rising adoption of single-use bioprocessing, and increasing industry collaborations. Key trends include R&D investments, technological advancements, development of new technologies, and advanced filtration techniques.

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Which Upcoming Market Trends and Innovations Are Set to Influence theUpstream Bioprocessing Market’s Path Forward?

Companies in the upstream bioprocessing market are developing advanced bioreactors to improve cell culture processes. For instance, in April 2023, Cytiva, a US-based life sciences provider, introduced X-platform bioreactors for upstream bioprocessing. These modular bioreactors streamline single-use procedures, offering a user-friendly design and an online Bioreactor Scaler tool for optimal scale-up parameters.

Who Are the Dominant Market Players Pushing the Boundaries of theUpstream Bioprocessing Market?

Major companies operating in the upstream bioprocessing market are Thermo Fisher Scientific Inc., Danaher Corp, Merck KGaA, GE HealthCare Technologies, Parker Hannifin Corp, Corning Inc., AGC Biologics, Avantor, AGC Inc., Boehringer Ingelheim International GmbH, Catalent Inc., Sartorius AG, Entegris Inc., Getinge AB, Bio-Rad Laboratories Inc., Samsung Biologics Co. Ltd., Eppendorf AG, Repligen Corporation, Takara Bio Inc., KBI Biopharma Inc., Rentschler Biopharma SE, Just Biotherapeutics Inc., PBS Biotech Inc., Stobbe Group, Applikon Biotechnology

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What Are the Core Segments of the Upstream Bioprocessing Market, and How Do They Contribute to Growth?

The upstream bioprocessing market covered in this report is segmented –

1) By Product type: Bioreactors, Fermenters, Cell Culture Media, Filters, Bags And Containers

2) By Workflow: Media Preparation, Cell Culture, Cell Separation

3) By Usage type: Single-Use, Multi-Use

4) By Mode: In House, Outsourced

5) By End User: Contract Development and Manufacturing Organization (CDMOs) Or Contract Research Organization (CROs), Research And Academic Institutes, Biopharmaceutical Companies

Subsegments:

1) By Bioreactors: Single-Use Bioreactors, Multi-Use Bioreactors

2) By Fermenters: Laboratory Fermenters, Pilot Scale Fermenters, Industrial Fermenters

3) By Cell Culture Media: Powdered Media, Liquid Media

4) By Filters: Sterile Filters, Air Filters, Capsule Filters

5) By Bags And Containers: Single-Use Bags, Bioprocess Containers, Storage Bags

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What Regions Are Dominating the Upstream Bioprocessing Market Growth?

North America was the largest region in the upstream bioprocessing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the upstream bioprocessing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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