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What key factors are powering the surge in the zynteglo market right now?

In recent years, the size of the Zynteglo market has expanded with an HCAGR of XX. Forecasts anticipate that it will rise from $XX million in 2024 to $XX million in 2025, marking a compound annual growth rate (CAGR) of XX%. This upward trend during the historical period is likely due to several factors. These include a rise in rare genetic disorders, a growing interest in personalized medicine, escalated investment in gene therapy studies, heightened regulatory clearance for gene therapies, and an increasing prevalence of numerous chronic diseases.

How fast Is the zynteglo market expected to grow, and what’s its future value?

In the coming years, the market size for Zynteglo is anticipated to experience an increase of XX (FCAGR). By 2029, predictions suggest it will have grown to a substantial $XX million, showing a Compound Annual Growth Rate (CAGR) of XX%. Factors contributing to this projected increase within the forecast period include a higher occurrence of thalassemia, improved healthcare infrastructure, and an enlarging patient demographic for rare diseases. In addition, there is a growing interest in long-lasting treatment solutions and an increased willingness to accept more expensive treatments. Key trends within this period are expected to include advancements in the field of genetic editing technology, the development of sophisticated treatments, incorporation of patient data to tailor treatments, innovative methods in clinical trials, and the adoption of advanced gene-editing technologies.

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What are the leading drivers of growth in the zynteglo market?

The escalating frequency of thalassemia is anticipated to fuel the expansion of the zynteglo market in the future. Thalassemia is a group of inherited blood disorders in which the body does not produce sufficient hemoglobin, causing anemia. This growth in thalassemia cases can be ascribed to factors such as elevated carrier rates in specific demographics, genetic transmission through inter-family marriages, increased migration, lack of knowledge and screening, and enhanced diagnosis and survival rates. Zynteglo offers a solution to mitigate thalassemia incidents by offering a one-time gene therapy that equips patients to produce healthy hemoglobin, possibly eliminating the necessity for regular blood transfusions. For instance, data released in November 2024 by the American Society of Hematology, a professional organization based in the US, revealed that the prevalence of beta-thalassemia in 2023 was roughly 3,665 cases, implying a rate of 1.07 per 100,000 individuals. Hence, the escalation in thalassemia cases contributes to the expansion of the zynteglo market.

What are the key segments defining the zynteglo market?

The zynteglo market covered in this report is segmented –

1) By Indication: Beta -Thalassemia; Sickle Cell Disease

2) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies

3) By End User: Adult; Pediatric; Geriatric

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Who are the key players steering the development of the zynteglo market?

Major companies operating in the zynteglo market are Bluebird bio Inc

What emerging trends are influencing the growth of the zynteglo market?

In the zynteglo market, a pivotal trend is the development of cutting-edge therapies, including gene therapies, which are designed to treat genetic disorders with sustained effectiveness. Gene therapies are medical treatments which involve modifying the genes within a patient’s cells in order to treat or ward off diseases, usually through the correction of malfunctioning genes or the introduction of new genetic material to fight or inhibit diseases. For example, in August 2022, US biotech company Bluebird Bio Inc. received approval from the Food and Drug Administration (FDA) for ZYNTEGLO (betibeglogene autotemcel), a landmark one-off gene therapy intended to treat beta-thalassemia, a hereditary blood disorder. This approval signifies a major advance in gene therapy, as ZYNTEGLO is the first ex-vivo lentiviral vector gene therapy to be given the green light by the FDA for treating beta-thalassemia. The therapy functions by altering a patient’s stem cells to produce functional hemoglobin, potentially eradicating the need for regular red blood cell transfusions and iron chelation therapy.

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Which regions are most influential in expanding the zynteglo market?

North America was the largest region in the zynteglo market in 2024. The regions covered in the zynteglo market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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