Medical Equipment

Normothermic Machine Perfusion Market Developments And Opportunities Across 2026–2030

April 14, 2026 by Marketing Posting

The Business Research Company’s 2026 market reports feature enhanced tools like market attractiveness analysis, TAM assessment, and company scoring matrices, along with interactive dashboards, deeper supply chain insights, and startup coverage strengthening the depth, usability, and strategic value of insights.

From Its 2026 Market Size, What Value Is The Normothermic Machine Perfusion Market Projected To Reach By 2030? _x000D_

The normothermic machine perfusion market has experienced rapid expansion in recent years. Its size is projected to increase from $1.48 billion in 2025 to $1.72 billion in 2026, exhibiting a compound annual growth rate (CAGR) of 16.2%. Historically, this growth can be attributed to several factors including limited organ preservation technologies, a dependence on cold storage methods, a shortage of transplantable organs, the rising number of organ transplant procedures, and the initial integration of stationary perfusion machines._x000D_

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The normothermic machine perfusion market is anticipated to experience substantial expansion in the coming years. This market is projected to reach $3.12 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 16.0%. Key drivers for this growth include the emergence of portable and battery-operated machines, advancements in mechanical circulation and oxygenation technologies, a global increase in demand for organ transplantation, the incorporation of smart monitoring systems, and the broadening of research and development efforts in organ preservation. Significant trends anticipated during this period involve the increasing uptake of portable normothermic machines, an intensified focus on organ viability and prolonged preservation, the integration of sophisticated monitoring and oxygenation technologies, the enlargement of organ transplantation programs, and a greater utilization in research and development applications._x000D_

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What Leading Drivers Are Supporting The Normothermic Machine Perfusion Market Expansion?_x000D_

The normothermic machine perfusion market is anticipated to expand as a result of the rising demand for organ transplantation. This medical procedure involves replacing a diseased or non-functioning organ with a healthy one from another individual. The increase in organ transplantation is primarily driven by the growing occurrence of end-stage organ failure, often caused by chronic illnesses, combined with improvements in surgical and immunosuppressive techniques. Within organ transplantation, normothermic machine perfusion is utilized to preserve and revive donor organs by sustaining them at body temperature with oxygenated blood or perfusate until the transplant occurs. For example, in January 2024, the U.S. Department of Health & Human Services, a US-based government department, reported that 46,632 organ transplants from both living and deceased donors were performed in 2023, which signifies an 8.7% increase compared to 2022. Therefore, the increasing need for organ transplantation is a significant factor propelling the growth of the normothermic machine perfusion market._x000D_

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How Is Segmentation Applied In The Normothermic Machine Perfusion Market Segment Analysis?_x000D_

The normothermic machine perfusion market covered in this report is segmented – _x000D_

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1) By Product Type: Portable Normothermic Machine, Stationary Normothermic Machine _x000D_

2) By Technology: Mechanical Circulation Technology, Oxygenation Technology, Monitoring Technology _x000D_

3) By Application: Organ Preservation, Organ Transplantation, Research And Development_x000D_

4) By End-User: Hospitals And Ambulatory Surgery Centers (ASCs), Specialty Clinics, Other End-Users_x000D_

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Subsegments:_x000D_

1) By Portable Normothermic Machine: Compact Portable, Battery-Operated Portable Machines, Transport-Friendly Portable Units_x000D_

2) By Stationary Normothermic Machine: In-Hospital Stationary Machines, Modular Stationary Systems, Advanced Fixed-Location Units_x000D_

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What Emerging Trends Are Seen In The Normothermic Machine Perfusion Market?_x000D_

Major companies engaged in the normothermic machine perfusion market are concentrating on establishing advanced research facilities to foster innovation, strengthen organ preservation technologies, and enhance transplant success. Expanding facilities in normothermic machine perfusion boosts capacity for organ preservation, research, and clinical application, leading to improved transplant outcomes and availability. As an illustration, in May 2024, OrganOx Ltd., a UK-based medical equipment manufacturing firm, opened an 18,000 sq. ft. global research and development and production facility in Oxford. This expansion aims to extend innovation and partnerships, following the successful worldwide impact of its metra device on liver transplant outcomes. The facility represents a positive step towards driving scientific and clinical innovation through technology for more effective treatment of organ failure._x000D_

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Who Are The Companies Participating In The Normothermic Machine Perfusion Market Environment?_x000D_

Major companies operating in the normothermic machine perfusion market are TransMedics Inc., OrganOx Limited, XVIVO Perfusion AB, Organ Recovery Systems Inc., Bridge to Life Ltd., Paragonix Technologies Inc., Lifeline Scientific Inc., LifePort Inc., XENIOS AG, Lung Bioengineering Inc., Waters Medical Systems LLC, Organ Assist B.V., Preservation Solutions Inc., Perfusix AB, Fluent Medical Inc., HemoTherapeutics Inc., Revivicor Inc., Transplant Solutions Inc., BioMedica Diagnostics (Organ Perfusion Division), Advanced Perfusion Systems Inc., Organ Preservation Alliance Technologies, NormaTech Medical Systems _x000D_

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Which Region Has The Greatest Market Share In The Normothermic Machine Perfusion Market?_x000D_

North America was the largest region in the normothermic machine perfusion market in 2025. The regions covered in the normothermic machine perfusion market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa._x000D_

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