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How has the small molecule drug discovery market grown over the years?

The market size of small molecule drug discovery has seen substantial growth in the past few years. The market, which is expected to be valued at $62.44 billion in 2024, is projected to expand to $68.57 billion in 2025, experiencing a compound annual growth rate (CAGR) of 9.8%. Factors contributing to this significant growth during the historical period include initiatives for drug repurposing, automation advancements in drug discovery, augmented investment in research & development, regulatory backing for drug evolution, and improvements in high-throughput screening.

What Is the forecasted market size and growth rate for the small molecule drug discovery market?

The market size for small molecule drug discovery is predicted to witness substantial expansion in the upcoming years. It is projected to reach $106.91 billion by 2029, increasing at a compound annual growth rate (CAGR) of 11.7%. The enhancement during the predicted timeframe can be credited to the development of new therapeutic targets, drug discovery that focuses on patients’ requirements, the combination of drug and device products, the application of real-world evidence, the integration of pharmacogenomics, and worldwide health issues. Notable trends that will shape the forecast period encompass fragment-oriented drug discovery, the application of artificial intelligence in drug discovery, RNA-focused therapies, collaborations and alliances, advancements in drug delivery, and the adoption of organoids and 3D cell culture models.

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What are the major factors driving growth in the small molecule drug discovery market?

The surge in chronic disease cases is anticipated to propel the small molecule drug discovery market’s expansion in the future. Chronic diseases are long-lasting conditions that impede daily activities and require ongoing medical attention. Small-molecule drugs serve as effective treatments for chronic diseases such as HIV, cancer, infections, heart disease, and kidney disease, typically presenting a more cost-effective solution for those suffering from such conditions. As a result, the increasing prevalence of chronic illnesses is set to enhance the small molecule drug discovery market. For example, the National Institutes of Health (NIH), an American biomedical research institution, revealed in a 2023 report that the population aged over 50 with at least one chronic disease in the United States is anticipated to increase by 99.5%, from 71.522 million in 2020 to 142.66 million by 2050. Concurrently, the population suffering from multimorbidity is projected to escalate 91.16%, from 7.8304 million in 2020 to 14.968 million in 2050. Therefore, the escalating prevalence of chronic diseases is propelling the development of the small molecule drug discovery market.

What key areas define the segmentation of the global small molecule drug discovery Market?

The small molecule drug discovery market covered in this report is segmented –

1) By Drug Type: Small Molecule Drugs, Biologic Drugs

2) By Technology: High Throughput Screening, Pharmacogenomics, Combinatorial Chemistry, Nanotechnology, Others

3) By Therapeutic Area: Oncology, Central Nervous System, Cardiovascular, Respiratory, Metabolic Disorders, Gastrointestinal, Others

4) By Process Or Phase: Target ID Or Validation, Hit Generation And Selection, Lead Identification, Lead Optimization

5) By End-User: Pharmaceutical Companies, Contract Research Organizations, Others

Subsegments:

1) By Small Molecule Drugs: Generic Small Molecule Drugs, Novel Small Molecule Drugs

2) By Biologic Drugs: Monoclonal Antibodies, Vaccines, Recombinant Proteins, Cell And Gene Therapies

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What are the top market players propelling the growth of the small molecule drug discovery industry?

Major companies operating in the small molecule drug discovery market include Pfizer Inc., GlaxoSmithKline plc, AstraZeneca, Boehringer Ingelheim International GmbH, Bristol-Myers Squibb Company, Johnson & Johnson, Gilead Sciences Inc., Merck KGaA, Novartis AG, 4SC AG, Teva Pharmaceutical Industries Ltd., Takeda Pharmaceutical Company Limited, Labcorp Drug Development, ICON Public Limited Company, Charles River Laboratories, Aluda Pharmaceuticals, Clinuvel Pharmaceuticals, Corcept Therapeutics, Edison Oncology, Escend Pharmaceuticals, Terray Therapeutics, Apollomics, Astex Pharmaceuticals, Pardes Biosciences, Xynomic Pharmaceuticals, Zevra Therapeutics, UNION therapeutics, Pharmacosmos, Allarity Therapeutics, Xellia Pharmaceuticals, Cyteir Therapeutics, BigHat Biosciences

What are the key trends shaping the future of the small molecule drug discovery market?

Innovations within the realm of technology are becoming a prominent trend in the small molecule drug discovery market. Predominant businesses in this sector are increasingly concentrated on the creation of novel products. For example, Dotmatics, an American digital science platform provider, unveiled its Small Molecule Drug Discovery Solution in January 2023. This exceptional design integrates a scientific R&D platform with pre-established workflows and enhanced data management capabilities. It mitigates operational issues while hastening the process of transforming data into actionable insights and decisions.

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What regions are dominating the small molecule drug discovery market growth?

North America was the largest region in the small molecule drug discovery market in 2024. Europe is expected to be the fastest-growing region in the small molecule drug discovery market report during the forecast period. The regions covered in the small molecule drug discovery market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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