Global Pyrogen Testing Market
Healthcare Services

Pyrogen Testing Market Forecast and Insights: Exploring Growth Trends, Market Size, and Emerging Opportunities

2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

What External and Internal Drivers Are Contributing to the Growth of thePyrogen Testing Market?

The increasing investments in pharmaceutical and biotechnology research and development are contributing to the growth of the pyrogen testing market. Pyrogen testing is crucial for ensuring the safety of pharmaceutical products and preventing infections. According to the Association of the British Pharmaceutical Industry, the UK allocated approximately £9 billion for pharmaceutical R&D in 2022, boosting the demand for pyrogen testing services.

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#What is the Growth Potential of the Pyrogen Testing Market, and How Will It Perform by 2034?

The pyrogen testing market has experienced rapid growth in recent years. It will rise from $1.68 billion in 2024 to $1.91 billion in 2025, with a compound annual growth rate (CAGR) of 13.8%. This growth is driven by the expansion of the pharmaceutical and biotechnology industries, regulatory requirements for drug safety, advancements in testing methods, increased infectious disease outbreaks, and the adoption of pyrogen testing in medical device manufacturing.

The pyrogen testing market is forecasted to grow to $3.1 billion by 2029, at a CAGR of 12.8%. The growth is driven by custom testing solutions, rapid testing advancements, in vitro detection innovation, and pyrogen testing in cell therapy. Trends include point-of-care testing, AI-driven detection, regulatory compliance, and patient-specific testing solutions.

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Which Upcoming Market Trends and Innovations Are Set to Influence thePyrogen Testing Market’s Path Forward?

Companies are focusing on the development of animal-free pyrogen testing methods, such as the monocyte activation assay (MAT), to address the limitations of rabbit pyrogen testing and the LAL test, ultimately aiming to eliminate animal use in human treatments. MAT provides superior pyrogenic activity prediction and better stimulates fever responses compared to the Rabbit Pyrogen Test (RPT) or the BET/LAL test. MAT can detect both endotoxin and non-endotoxin pyrogens, unlike the LAL test, which is limited to detecting endotoxins. For example, Merck is focusing on two MAT systems—PyroDetect and PyroMAT—for pyrogen detection.

Who Are the Dominant Market Players Pushing the Boundaries of thePyrogen Testing Market?

Major companies operating in the pyrogen testing market include Thermo Fisher Scientific Inc., Merck KGaA, Charles River Laboratories Inc., Lonza Group Ltd., Ellab A/S, Nelson Laboratories LLC, Associates of Cape Cod Inc., GenScript Biotech Corporation, bioMérieux SA, Hyglos GmbH, Sanquin Blood Supply Foundation, Wako Chemicals USA Inc., Pyrostar International Inc., Eurofins Scientific SE, SGS SA, WuXi AppTec Group, Sigma-Aldrich Co. LLC, Bio-Rad Laboratories Inc., Microcoat Biotechnologie GmbH, Sartorius AG, Pacific Biolabs Inc., Toxikon Corporation, STERIS Corporation, Avance Biosciences Inc., BioReliance Corporation, Microbiological Consulting LLC, Microbac Laboratories Inc., North American Science Associates Inc., Pace Analytical Life Sciences LLC

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What Are the Core Segments of the Pyrogen Testing Market, and How Do They Contribute to Growth?

The pyrogen testing market covered in this report is segmented –

1) By Test Type: LAL Test, In Vitro Test, Rabbit Test

2) By Product And Service: Assays, Kits, And Reagents, Instruments, Services

3) By Application: Pharmaceutical And Biologics, Medical Devices, Other Applications

Subsegments:

1) By Test Limulus Amebocyte Lysate (LAL) Test: Gel Clot LAL Test, Chromogenic LAL Test, Turbidimetric LAL Test

2) By In Vitro Test: Monocyte Activation Test (MAT), Recombinant Factor C (rFC) Assay, Other In Vitro Tests

3) By Rabbit Test: Pyrogen Test in Rabbits, Other Animal-Based Tests

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What Regions Are Dominating the Pyrogen Testing Market Growth?

North America was the largest region in the pyrogen testing market in 2024. Asia-Pacific is expected to continue to be the fastest growing region in the pyrogen testing market share during the forecast period. The regions covered in the pyrogen testing market report include Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

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