2025 Market Reports Update: Market Size Forecasts to 2034, Key Trends, Leading Players, and Top Regions – Get Ahead of the Competition Today!

Which Major Market Drivers Are Expected to Boost the Growth Potential of the Primary Biliary Cholangitis Market?

The primary biliary cholangitis market is predicted to expand due to the rising rates of smoking. The process of inhaling and exhaling smoke from burned tobacco or similar substances, also known as smoking, is a recognized contributor to liver diseases such as PBC. As smoking rises, so does the number of individuals seeking treatment for liver-related problems. For example, in July 2023, Statistics Canada, a government organization, reported a 2.2% increase in cigarette production compared to June 2023. Moreover, cigarette sales increased by 2.6% to reach 1.4 billion units in June compared to May. Hence, increased smoking rates will boost the primary biliary cholangitis market. The primary biliary cholangitis market is also projected to grow due to an upsurge in liver cancer cases. Liver cancer, a disease that originates in the liver cells, is a significant risk factor for primary biliary cholangitis due to an increased risk of various cancers, including cholangiocarcinoma and hepatocellular carcinoma. The increasing incidence of this disease and its potential complications are expected to fuel the market’s growth. For example, in January 2024, the American Cancer Society predicted about 41,630 new liver cancer cases, with 28,000 cases in men and 13,630 in women. They also estimate that about 29,840 individuals (19,120 men and 10,720 women) are likely to die from this disease. Therefore, the rise in liver cancer cases is expected to stimulate the growth of the primary biliary cholangitis market.

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#What is the Projected CAGR for the Primary Biliary Cholangitis Market Size from 2025 to 2034?

The market size for primary biliary cholangitis has experienced swift growth in the previous years. A surge from $0.98 billion in 2024 to $1.09 billion in 2025 with a compound annual growth rate (CAGR) of 11.8% is projected. Factors such as heightened disease consciousness, an elevating global healthcare budget, strategic partnerships within the healthcare industry, an emphasis on patient advocacy, and governmental drives for liver health have fueled the growth during the historical period.

Over the upcoming years, the market size for primary biliary cholangitis is anticipated to witness considerable growth, reaching $1.6 billion in 2029 with a compound annual growth rate (CAGR) of 9.9%. This surge during the predicted period is linked to the expansion of biomarker studies, global initiatives towards managing rare diseases, increased collaboration in clinical trials, and patient-focused healthcare strategies, along with the growing demand for liver transplants. The future trends include enhanced focus on non-invasive diagnostic methods, progress in biomarker research, emphasis on immunomodulatory treatments, application of artificial intelligence (AI), evaluations based on patient feedback in clinical trials, utilising telemedicine for patient care, focus on combination therapies, and the introduction of treatments targeting fibrosis.

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What Are the Key Market Innovations in thePrimary Biliary Cholangitis Market Over the Coming Years?

Firms engaged in the primary biliary cholangitis market are concentrating their efforts on generating new and specific therapies, such as orphan drugs that include obeticholic acid (OCA) and bezafibrates to manage primary biliary cholangitis (PBC). The aim of designating the mixture of OCA and bezafibrate as an orphan drug is to offer a more encompassing and effective solution for PBC care, potentially enhancing the life of those struggling with this uncommon disease. For instance, in May 2023, Intercept Pharmaceuticals, Inc., an American biopharmaceutical enterprise, was acknowledged by the FDA with an orphan drug designation for the blend of obeticholic acid (OCA) and bezafibrate, a PPAR agonist. This is anticipated to serve as a viable treatment for primary biliary cholangitis (PBC), a steadily advancing liver disorder. Obeticholic acid, under the brand name Ocaliva, is already approved for PBC in the United States.

Who Are the Top Companies Driving Innovation and Growth in thePrimary Biliary Cholangitis Market?

Major companies operating in the primary biliary cholangitis market report are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck And Co. Inc., Novartis AG, Bristol-Myers Squibb Company, AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company, Amgen Inc., Boehringer Ingelheim International GmbH., Gilead Sciences Inc., Vertex Pharmaceuticals, Dr. Reddy’s Laboratories Ltd., Amneal Pharmaceuticals LLC, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Intercept Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., CureVac N.V., Sangamo Therapeutics Inc., Calliditas Therapeutics AB, NGM Biopharmaceuticals Inc., Bluebird Bio Inc., Intellia Therapeutics Inc., Albireo Pharma Inc., TARGET PharmaSolutions Inc., Genfit S.A., Editas Medicine Inc., CymaBay Therapeutics Inc., Ascletis Pharma Inc.

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Which Key Market Segments Comprise the Primary Biliary Cholangitis Market and Drive Its Revenue Growth?

The primary biliary cholangitis market covered in this report is segmented –

1) By Treatment Type: Drugs, Liver Transplantation

2) By Diagnosis: Imaging Tests, Magnetic Resonance Elastography (MRE), Magnetic Resonance Cholangiopancreatography (MRCP), Ultrasound, Fibroscan, Blood Tests, Cholesterol Test, Antibody Tests, Liver Tests, Other Diagnoses

3) By End-Users: Specialty Clinics, Homecare, Other End-Users

Subsegments:

1) By Drugs: Ursodeoxycholic Acid (UDCA), Obeticholic Acid (OCA), Fibrates, Immunosuppressive Drugs, Other Targeted Therapies

2) By Liver Transplantation: Orthotopic Liver Transplantation (OLT), Living Donor Liver Transplantation, Hepatobiliary Surgery For Liver Transplant

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Which Regions Are Emerging as Leaders in the Primary Biliary Cholangitis Market?

North America was the largest region in the primary biliary cholangitis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the primary biliary cholangitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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